Transcription Factor
| Accessions: | A8MT65 (JASPAR 2024) |
| Names: | ZN891_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | A8MT65 |
| Length: | 544 |
| Pfam Domains: | 43-83 KRAB box 314-331 Zinc-finger double domain 320-336 C2H2-type zinc finger 337-358 Zinc-finger double domain 348-370 C2H2-type zinc finger 348-370 Zinc finger, C2H2 type 348-370 C2H2-type zinc finger 363-386 Zinc-finger double domain 375-398 C2H2-type zinc finger 376-398 Zinc finger, C2H2 type 376-398 C2H2-type zinc finger 390-415 Zinc-finger double domain 403-424 C2H2-type zinc finger 404-426 Zinc finger, C2H2 type 404-426 C2H2-type zinc finger 421-443 Zinc-finger double domain 431-452 C2H2-type zinc finger 432-454 Zinc finger, C2H2 type 432-454 C2H2-type zinc finger 446-470 Zinc-finger double domain 459-482 C2H2-type zinc finger 460-482 Zinc finger, C2H2 type 460-482 C2H2-type zinc finger 474-498 Zinc-finger double domain 487-504 C2H2-type zinc finger 488-510 Zinc finger, C2H2 type 488-510 C2H2-type zinc finger 502-526 Zinc-finger double domain 515-536 C2H2-type zinc finger 516-538 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MAVMDLSSPWALTKQDSACFHLRNAEEERMIAVFLTTWLQEPMTFKDVAVEFTQEEWMML 60 61 DSAQRSLYRDVMLENYRNLTSVEYQLYRLTVISPLDQEEIRNMKKRIPQAICPDQKIQPK 120 121 TKESTVQKILWEEPSNAVKMIKLTMHNWSSTLREDWECHKIRKQHKIPGGHWRQMIYAPK 180 181 KTVPQELFRDYHELEENSKLGSKLIFSQSIFTSKHCQKCYSEIGCLKHNSIINNYVKNSI 240 241 SEKLYESHECDTTLWHFQRNQTVQKEYTYSKHGMHFTHNMFPVPNNLHMAQNACECNKDE 300 301 TLCHQSSLKKQGQTHTEKKHECNQCGKAFKRISNLTLYKKSHMGEKQYECKECGKVFNDS 360 361 STLRRHVRTHTGEKPYECNQCGKAFSQKTSLKAHMRTHTGEKPYECNQCGKSFGTSSYLI 420 421 VHKRIHTGEKLYECSECGKAFNTSSHLKVHKKIHTGENVYECSDCGKVFSGVSSLRMHIR 480 481 THTGEKPYECKECRKAFSVSSSLRRHVRIHTGEKPYECIQCGKAFSQSSSLIIHKRIHTE 540 541 RETL |
| Interface Residues: | 306, 310, 330, 331, 332, 333, 334, 337, 338, 348, 358, 359, 360, 361, 362, 363, 364, 365, 366, 386, 387, 388, 389, 390, 392, 393, 397, 414, 415, 416, 417, 418, 421, 442, 443, 444, 445, 446, 448, 449, 451, 452, 455, 470, 471, 472, 473, 474, 475, 477, 480, 498, 499, 500, 501, 502, 504, 505, 511, 525, 527, 528, 529, 530, 532, 533, 537 |
| 3D-footprint Homologues: | 7w1m_H, 6u9q_A, 8ssu_A, 8ssq_A, 4m9v_C, 7ysf_A, 2kmk_A, 8cuc_F, 7y3l_A, 7n5w_A, 3uk3_C, 4x9j_A, 5kkq_D, 8gn3_A, 5ei9_F, 1g2f_F, 5kl3_A, 5k5i_A, 5v3j_F, 2drp_D, 6blw_A, 8h9h_G, 7y3m_I, 5yel_A, 1ubd_C, 5k5l_F, 1tf6_A, 7txc_E, 1llm_D, 2lt7_A, 6e94_A, 2wbs_A, 2gli_A, 6ml4_A, 2jpa_A, 1tf3_A, 6jnm_A, 6a57_A, 1f2i_J, 5yj3_D |
| Binding Motifs: | UN0666.1 gykmvcmGgCtTCyAGCC UN0666.2 GgCtTCyAGCC |
| Related annotations: | PaperBLAST |
Disclaimer and license
These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.