Transcription Factor

Accessions: UP00122A (UniPROBE 20160601)
Names: Not Available, TGFB-induced factor 2, Tgif1
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: Not Av
Description: TGFB-induced factor 2
Length: 96
Pfam Domains: 17-73 Homeobox domain
34-73 Homeobox KN domain
Sequence:
(in bold interface residues)
1 SMDSPLDLSSSAASGKRRRRGNLPKESVQILRDWLYEHRYNAYPSEQEKALLSQQTHLST 60
61 LQVCNWFINARRRLLPDMLRKDGKDPNQFTISRRGA
Interface Residues: 17, 18, 19, 20, 64, 65, 68, 69, 70, 72, 73, 87, 88, 89, 92, 93
3D-footprint Homologues: 6fqp_B, 1zq3_P, 1puf_B, 4j19_B, 1le8_A, 1mnm_C, 6fqq_E, 2hdd_A, 1k61_B, 4xrm_B, 7psx_B, 5zjt_E, 1du0_A, 1le8_B, 2d5v_B, 1fjl_B, 2hos_A, 2p5l_D
Binding Motifs: UP00122A_1 dakwwTGACAGCTsskw
Binding Sites: AACTGTCA
AATGACAG
ACCTGTCA
ACTGACAG
AGCTGTCA
ATCTGTCA
ATGACAGC
ATTGACAG
CCTGTCAA
CGCTGTCA
CTGACAGC
CTGTCAAA
CTGTCAAC
CTGTCAGA
GCTGTCAA
GCTGTCAC
GGCTGTCA
TCCTGTCA
TCTGTCAA
TGACAGCA
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.