Transcription Factor
Accessions: | 1a66_A (3D-footprint 20231221) |
Names: | CORE NFATC1, NF-ATc1, NFAC1_HUMAN, NFAT transcription complex cytosolic component, Nuclear factor of activated T-cells, cytoplasmic 1 |
Organisms: | Homo sapiens |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | O95644 |
Length: | 178 |
Pfam Domains: | 15-175 Rel homology domain (RHD) |
Sequence: (in bold interface residues) | 1 MKDWQLPSHSGPYELRIEVQPKSHHRARYETEGSRGAVKASAGGHPIVQLHGYLENEPLM 60 61 LQLFIGTADDRLLRPHAFYQVHRITGKTVSTTSHEAILSNTKVLEIPLLPENSMRAVIDC 120 121 AGILKLRNSDIELRKGETDIGRKNTRVRLVFRVHVPQPSGRTLSLQVASNPIECSQRS |
Interface Residues: | 26, 28, 29, 31, 32, 35, 125, 142, 176, 177 |
3D-footprint Homologues: | 2ram_A, 1imh_C, 1p7h_L, 2o61_A, 1a66_A |
Binding Motifs: | 1a66_A GAGGAana |
Binding Sites: | 1a66_B 1a66_C |
Publications: | Zhou P., Sun L. J., Doetsch V., Wagner G., Verdine G. L. Solution structure of the core NFATC1/DNA complex.. Cell 92:687-696 (1998). [Pubmed] |
Related annotations: | PaperBLAST |
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