Transcription Factor
| Accessions: | P58317 (JASPAR 2024) |
| Names: | Zinc finger protein 121, Zinc finger protein 20, ZN121_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P58317 |
| Length: | 390 |
| Pfam Domains: | 135-154 Zinc-finger double domain 143-166 C2H2-type zinc finger 144-166 C2H2-type zinc finger 144-166 Zinc finger, C2H2 type 159-182 Zinc-finger double domain 171-181 C2H2-type zinc finger 172-194 C2H2-type zinc finger 172-194 Zinc finger, C2H2 type 186-210 Zinc-finger double domain 200-222 Zinc finger, C2H2 type 200-222 C2H2-type zinc finger 200-218 C2H2-type zinc finger 215-238 Zinc-finger double domain 227-246 C2H2-type zinc finger 228-250 Zinc finger, C2H2 type 228-250 C2H2-type zinc finger 243-266 Zinc-finger double domain 255-267 C2H2-type zinc finger 256-278 Zinc finger, C2H2 type 256-278 C2H2-type zinc finger 271-294 Zinc-finger double domain 283-293 C2H2-type zinc finger 284-306 Zinc finger, C2H2 type 284-306 C2H2-type zinc finger 301-323 Zinc-finger double domain 311-334 C2H2-type zinc finger 312-334 Zinc finger, C2H2 type 312-334 C2H2-type zinc finger 328-349 Zinc-finger double domain 340-353 C2H2-type zinc finger 340-362 Zinc finger, C2H2 type 340-362 C2H2-type zinc finger 354-378 Zinc-finger double domain 368-390 C2H2-type zinc finger 368-390 C2H2-type zinc finger 368-390 Zinc finger, C2H2 type |
| Sequence: (in bold interface residues) | 1 MAEIHNGGELCDFMENGEIFSEHSCLNAHMGTENTGDTYDCDEYGENFPMLHNSAPAGET 60 61 LSVLNQCRKAFSLPPNVHQRTWIGDKSFEYSDCEEAFVDQSHLQANRITHNGETLYEQKQ 120 121 CGRAFTYSTSHAVSVKMHTVEKPYECKECGKFFRYSSYLNSHMRTHTGEKPYECKECGKC 180 181 FTVSSHLVEHVRIHTGEKPYQCKECGRAFAGRSGLTKHVRIHTGEKPYECNECGKAYNRF 240 241 YLLTEHFKTHTEEKPFECKVCGKSFRSSSCLKNHFRIHTGIKPYKCKECGKAFTVSSSLH 300 301 NHVKIHTGEKPYECKDCGKAFATSSQLIEHIRTHTGEKPYICKECGKTFRASSHLQKHVR 360 361 IHTGEKPYICNECGKAYNRFYLLTKHLKTH |
| Interface Residues: | 154, 155, 156, 157, 158, 161, 183, 184, 185, 186, 188, 189, 193, 210, 211, 212, 213, 214, 216, 217, 220, 239, 240, 241, 242, 244, 245, 256, 266, 267, 268, 269, 270, 272, 273, 274, 294, 295, 296, 297, 298, 299, 300, 301, 302, 303, 304, 307, 322, 323, 324, 325, 326, 329, 335, 349, 350, 351, 352, 353, 354, 356, 357, 361, 378, 379, 380, 381, 382, 384, 385 |
| 3D-footprint Homologues: | 3uk3_C, 7w1m_H, 7n5w_A, 5k5i_A, 8gn3_A, 5kl3_A, 1tf6_A, 8h9h_G, 6e94_A, 1g2f_F, 5v3j_F, 8ssq_A, 1llm_D, 2drp_D, 8ssu_A, 5kkq_D, 5yel_A, 2wbs_A, 6ml4_A, 7ysf_A, 2kmk_A, 4m9v_C, 2lt7_A, 1ubd_C, 7y3l_A, 6jnm_A, 7txc_E, 5ei9_F, 6blw_A, 6u9q_A, 5yj3_D, 4x9j_A, 2gli_A, 1f2i_J, 6a57_A, 2jpa_A, 1tf3_A, 7y3m_I, 8cuc_F |
| Binding Motifs: | UN0595.1 CTGGGCAACAkA |
| Binding Sites: | UN0595.1.1 UN0595.1.10 UN0595.1.11 UN0595.1.12 UN0595.1.13 UN0595.1.14 UN0595.1.15 UN0595.1.16 UN0595.1.17 UN0595.1.18 UN0595.1.19 UN0595.1.2 UN0595.1.20 UN0595.1.3 UN0595.1.4 UN0595.1.5 UN0595.1.6 UN0595.1.7 UN0595.1.8 UN0595.1.9 |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.