Transcription Factor

Accessions: T081617_1.02 (CISBP 1.02)
Names: FOXO4, T081617_1.02;
Organisms: Homo sapiens
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: family:Forkhead
Length: 450
Pfam Domains: 54-130 Fork head domain
Sequence:
(in bold interface residues)
1 MDPGNENSATEAAAIIDLDPDFEPQSRPRSCTWPLPRPEIANQPSEPPEVEPDLGEKAIE 60
61 SAPEKRLTLAQIYEWMVRTVPYFKDKGDSNSSAGWKNSIRHNLSLHSKFIKVHNEATGKS 120
121 SWWMLNPEGGKSGKAPRRRAASMDSSSKLLRGRSKAPKKKPSVLPAPPEGATPTSPVGHF 180
181 AKWSGSPCSRNREEADMWTTFRPRSSSNASSVSTRLSPLRPESEVLAEEIPASVSSYAGG 240
241 VPPTLNEGLELLDGLNLTSSHSLLSRSGLSGFSLQHPGVTGPLHTYSSSLFSPAEGPLSA 300
301 GEGCFSSSQALEALLTSDTPPPPADVLMTQVDPILSQAPTLLLLGGLPSSSKLATGVGLC 360
361 PKPLEAPGPSSLVPTLSMIAPPPVMASAPIPKALGTPVLTPPTEAASQDRMPQDLDLDMY 420
421 MENLECDMDNIISDLMDEGEGLDFNFEPAP
Interface Residues: 69, 91, 93, 94, 96, 97, 98, 100, 101, 102, 104, 105, 114, 119, 138, 292
3D-footprint Homologues: 8vfz_O, 3l2c_A, 8bzm_E, 7vox_H, 2hdc_A, 2a07_J, 7yzb_A, 3co6_C, 7vou_C, 6ako_C, 2c6y_A, 7yze_A, 7cby_C, 3g73_A, 6el8_A, 7yzg_A, 7tdw_A, 7yz7_A, 6nce_A, 2uzk_A, 7tdx_A, 3qrf_G, 8sro_B, 6w64_A
Binding Motifs: M3282_1.02 rwAAACAagyy
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.