Transcription Factor

Accessions: T134689_1.02 (CISBP 1.02)
Names: nhr-216, T134689_1.02;
Organisms: Caenorhabditis elegans
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:Nuclear receptor
Length: 427
Pfam Domains: 60-128 Zinc finger, C4 type (two domains)
220-412 Ligand-binding domain of nuclear hormone receptor
Sequence:
(in bold interface residues)
1 MQSSSNIYIDPSMYPRYEYANLDISSFERSPTFEQPPSYPTYDQHVQFLPEIENNGPKQK 60
61 CRVCNLEAHGMHFGVQTCRPCAAFFRRIVVLDLKYTCVSNTQKCNVDGRGRNVCRDCRYK 120
121 KCIAVGMTTDNVQYNRDSHNNKNSSGSGGGRGRGKNKRNVMMMLTDEEEAAGSMMALHRL 180
181 PKTFGNCCFTGKFGRSTICRFCDTINAFTDGKAHLQRKSEKFSKWVKCVDFFDKLSDEQK 240
241 IDTVKMSFTVFDRLERAQMSVKIFGEKSITEKKTTLSSYCAVDWKNVKINPETAINTEQA 300
301 NNYVKAEFHAHVDSIIDEVCKPLYELQLSDTETAFILVQVLVYHGGEKVTPELVKMFDQL 360
361 RETIATDLHLYYTKESQTGTDTNRILKMMSVVNAMKKIHADRVRKSDLIQIFNIYKVSEK 420
421 RTDFNCS
Interface Residues: 69, 70, 72, 73, 79, 80, 82, 83, 86, 87, 112, 134, 136
3D-footprint Homologues: 6fbq_A, 6l6q_B, 7wnh_D, 1a6y_A, 1lo1_A, 3g9m_B, 4oln_B, 2a66_A, 2nll_B, 1lat_A, 7xv6_B, 2ff0_A, 1dsz_A, 4umm_E, 3cbb_A, 8cef_H, 4iqr_B, 2han_A, 1hcq_E, 8hbm_B, 5krb_G, 2han_B, 1kb2_B, 4tnt_B, 5e69_A, 4hn5_B, 5emc_A, 7prw_B, 5cbx_B, 3g6t_A, 1r4i_A, 5cbz_E
Binding Motifs: M1480_1.02 sTTCTGAYy
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.