Transcription Factor
| Accessions: | 4rod_B (3D-footprint 20231221), 4roe_B (3D-footprint 20231221) |
| Names: | TATA sequence-binding protein, TATA-binding factor, TATA-box factor, TATA-box-binding protein, TBP_HUMAN, Transcription initiation factor TFIID TBP subunit |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | P20226 |
| Length: | 177 |
| Pfam Domains: | 6-88 Transcription factor TFIID (or TATA-binding protein, TBP) 94-176 Transcription factor TFIID (or TATA-binding protein, TBP) |
| Sequence: (in bold interface residues) | 1 PSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSG 60 61 KMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTH 120 121 QQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKG |
| Interface Residues: | 10, 12, 40, 41, 55, 57, 63, 65, 99, 100, 102, 131, 132, 146, 148, 154, 156 |
| 3D-footprint Homologues: | 4wzs_D, 6cnb_R, 1cdw_A, 5iy6_P, 7z7n_D, 1qna_B, 5n9g_G, 1ytb_A, 5oqj_O, 1ais_A |
| Binding Motifs: | 4rod_AB GAnnCTTATATAnCTG 4roe_AB GAnnCTTATAAGnnc |
| Binding Sites: | 4rod_N 4rod_T 4roe_N 4roe_T |
| Publications: | Gouge J, Satia K, Guthertz N, Widya M, Thompson AJ, Cousin P, Dergai O, Hernandez N, Vannini A. Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2. Cell 163:1375-87 (2015). [Pubmed] |
| Related annotations: | PaperBLAST |
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