Transcription Factor
Accessions: | 4rod_B (3D-footprint 20231221), 4roe_B (3D-footprint 20231221) |
Names: | TATA sequence-binding protein, TATA-binding factor, TATA-box factor, TATA-box-binding protein, TBP_HUMAN, Transcription initiation factor TFIID TBP subunit |
Organisms: | Homo sapiens |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | P20226 |
Length: | 177 |
Pfam Domains: | 6-88 Transcription factor TFIID (or TATA-binding protein, TBP) 94-176 Transcription factor TFIID (or TATA-binding protein, TBP) |
Sequence: (in bold interface residues) | 1 PSGIVPQLQNIVSTVNLGCKLDLKTIALRARNAEYNPKRFAAVIMRIREPRTTALIFSSG 60 61 KMVCTGAKSEEQSRLAARKYARVVQKLGFPAKFLDFKIQNMVGSCDVKFPIRLEGLVLTH 120 121 QQFSSYEPELFPGLIYRMIKPRIVLLIFVSGKVVLTGAKVRAEIYEAFENIYPILKG |
Interface Residues: | 10, 12, 40, 41, 55, 57, 63, 65, 99, 100, 102, 131, 132, 146, 148, 154, 156 |
3D-footprint Homologues: | 5iy6_P, 7z7n_D, 1qna_B, 5n9g_G, 1ytb_A, 5oqj_O, 1ais_A, 4wzs_D, 6cnb_R, 1cdw_A |
Binding Motifs: | 4rod_AB GAnnCTTATATAnCTG 4roe_AB GAnnCTTATAAGnnc |
Binding Sites: | 4rod_N 4rod_T 4roe_N 4roe_T |
Publications: | Gouge J, Satia K, Guthertz N, Widya M, Thompson AJ, Cousin P, Dergai O, Hernandez N, Vannini A. Redox Signaling by the RNA Polymerase III TFIIB-Related Factor Brf2. Cell 163:1375-87 (2015). [Pubmed] |
Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.