Transcription Factor
Accessions: | 5d5v_D (3D-footprint 20231221) |
Names: | Heat shock factor protein 1, Heat shock transcription factor 1, HSF 1, HSF1_HUMAN, HSTF 1 |
Organisms: | Homo sapiens |
Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
Uniprot: | Q00613 |
Length: | 107 |
Pfam Domains: | 5-106 HSF-type DNA-binding |
Sequence: (in bold interface residues) | 1 SNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKYFKHNNMASFVRQ 60 61 LNMYGFRKVVHIEQGGVKPERDDTEFQHPCFLRGQEQLLENIKRKVT |
Interface Residues: | 50, 51, 56, 58, 59, 60, 62, 63, 104 |
3D-footprint Homologues: | 5hdn_C, 5d5w_B, 3hts_B, 4bqa_A, 5d5v_B, 7dci_A |
Binding Motifs: | 5d5v_BD GGAnTGGA |
Binding Sites: | 5d5v_A 5d5v_C |
Publications: | Neudegger T, Verghese J, Hayer-Hartl M, Hartl FU, Bracher A. Structure of human heat-shock transcription factor 1 in complex with DNA. Nat Struct Mol Biol 23:140-6 (2016). [Pubmed] |
Related annotations: | PaperBLAST |
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