DNA Binding Site
| Accessions: | 6edb_D (3D-footprint 20231221) |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Length: | 20 |
| Sequence: | CATTGTTTAGATCCCGGATC |
| Binding TFs: | 6edb_B (HMG (high mobility group) box, Domain of unknown function (DUF1898)) |
| Binding Motifs: | 6edb_AB cATTgkknnnnnCc 6edb_B AATg |
| Publications: | Xie W, Lama L, Adura C, Tomita D, Glickman JF, Tuschl T, Patel DJ. Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation. Proc Natl Acad Sci U S A 116:11946-11955 (2019). [Pubmed] |
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