DNA Binding Site

Accessions: 1b8i_C (3D-footprint 20231221), 4cyc_C (3D-footprint 20231221), 4uus_C (3D-footprint 20231221), 4uus_G (3D-footprint 20231221)
Organisms: Drosophila melanogaster
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 13
Sequence: CGCCATAAATCAC
Type: Heterodimer
Binding TFs: 1b8i_A (Homeobox domain)
1b8i_B (Homeobox domain, Homeobox KN domain)
4cyc_A (Homeobox domain)
4cyc_B (Homeobox domain, Homeobox KN domain)
4uus_B (Homeobox domain, Homeobox KN domain)
4uus_E (Homeobox domain)
Binding Motifs: 1b8i_A wTTATgG
1b8i_AB GTGATTTATGG
1b8i_B gTGAt
4cyc_A ATAa
4cyc_AB gTGAatTA
4cyc_B wnTCAc
4uus_AB cnATATATCA
4uus_E TTATGG
Publications: Passner J.M, Ryoo H.D, Shen L, Mann R.S, Aggarwal A.K. Structure of a DNA-bound Ultrabithorax-Extradenticle homeodomain complex. Nature 397:714-9 (1999). [Pubmed]

Foos N, Maurel-Zaffran C, Maté M.J, Vincentelli R, Hainaut M, Berenger H, Pradel J, Saurin A.J, Ortiz-Lombardía M, Graba Y. A flexible extension of the Drosophila ultrabithorax homeodomain defines a novel Hox/PBC interaction mode. Structure (London, England : 1993) 23:270-9 (2015). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.