DNA Binding Site
| Accessions: | CCAGATGG (UniPROBE 20160601), MA0668.3.11 (JASPAR 2024), MA0668.3.13 (JASPAR 2024), MA0668.3.17 (JASPAR 2024), MA0668.3.20 (JASPAR 2024), MA0668.3.3 (JASPAR 2024), MA0668.3.4 (JASPAR 2024), MA0668.3.6 (JASPAR 2024), MA0668.3.9 (JASPAR 2024), MA1109.2.10 (JASPAR 2024), MA1109.2.12 (JASPAR 2024), MA1109.2.14 (JASPAR 2024), MA1109.2.16 (JASPAR 2024), MA1109.2.3 (JASPAR 2024), MA1123.3.11 (JASPAR 2024), MA1123.3.14 (JASPAR 2024), MA1123.3.3 (JASPAR 2024), MA1123.3.7 (JASPAR 2024), MA1123.3.8 (JASPAR 2024), MA2170.1.17 (JASPAR 2024), MA2170.1.4 (JASPAR 2024), UN0733.1.5 (JASPAR 2024) |
| Organisms: | Caenorhabditis elegans, Mus musculus, Homo sapiens |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 8 |
| Sequence: | CCAGATGG |
| Type: | Heterodimer |
| Binding TFs: | UP00359A (Helix-loop-helix DNA-binding domain, Neuronal helix-loop-helix transcription factor ) UP00378A (Helix-loop-helix DNA-binding domain) UP00381A (Helix-loop-helix DNA-binding domain) UP00384A (Helix-loop-helix DNA-binding domain) Q13562 (Helix-loop-helix DNA-binding domain, Neuronal helix-loop-helix transcription factor ) Q15672 (Helix-loop-helix DNA-binding domain) Q62414 (Helix-loop-helix DNA-binding domain, Neuronal helix-loop-helix transcription factor ) Q10574 Q11094 Q13562 Q15672 Q62414 |
| Binding Motifs: | UP00359A_1 wkdraaaaraastm UP00378A_1 ctwwramwwwmmaw UP00381A_1 akwraTwagwaswm UP00359A_2 / UP00384A_2 mskaACAkCTGTyyaa UP00378A_2 / UP00384A_6 kktrmCAksTGkymmh UP00381A_2 / UP00384A_10 hmgamCAgcTGkymtc MA0668.3 aCAGATGG MA1109.2 aCAGATGG MA1123.3 CCAGATGt MA2170.1 ACAGrTGk UN0733.1 cCAGmTGg |
| Publications: | Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed] Fong AP, Yao Z, Zhong JW, Cao Y, Ruzzo WL, Gentleman RC, Tapscott SJ. Genetic and epigenetic determinants of neurogenesis and myogenesis. Dev Cell 22:721-35 (2012). [Pubmed] Sharma A, Moore M, Marcora E, Lee JE, Qiu Y, Samaras S, Stein R. The NeuroD1/BETA2 sequences essential for insulin gene transcription colocalize with those necessary for neurogenesis and p300/CREB binding protein binding. Mol Cell Biol 19:704-13 (1999). [Pubmed] Shukunami C, Takimoto A, Nishizaki Y, Yoshimoto Y, Tanaka S, Miura S, Watanabe H, Sakuma T, Yamamoto T, Kondoh G, Hiraki Y. Scleraxis is a transcriptional activator that regulates the expression of Tenomodulin, a marker of mature tenocytes and ligamentocytes. Sci Rep 8:3155 (2018). [Pubmed] Portman DS, Emmons SW. The basic helix-loop-helix transcription factors LIN-32 and HLH-2 function together in multiple steps of a C. elegans neuronal sublineage 127:5415-26 (Development.). [Pubmed] |
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