DNA Binding Site
| Accessions: | MA0481.4.6 (JASPAR 2024), MA0852.3.14 (JASPAR 2024), MA1103.3.15 (JASPAR 2024), MA1606.2.12 (JASPAR 2024) |
| Organisms: | Homo sapiens, Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 7 |
| Sequence: | GTAAACC |
| Type: | Heterodimer |
| Binding TFs: | Q01167 (Fork head domain, FHA domain) Q61080 (Fork head domain) P85037 (Fork head domain, FHA domain) Q9H334 (Fork head domain) P85037 Q01167 Q61080 Q9H334 |
| Binding Motifs: | MA0481.4 GTAAACA MA0852.3 GTAAACA MA1103.3 GTAAACA MA1606.2 rTAAACA |
| Publications: | Gabut M, Samavarchi-Tehrani P, Wang X, Slobodeniuc V, O'Hanlon D, Sung H.K, Alvarez M, Talukder S, Pan Q, Mazzoni E.O, Nedelec S, Wichterle H, Woltjen K, Hughes T.R, Zandstra P.W, Nagy A, Wrana J.L, Blencowe B.J. An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming. Cell 147:132-46 (2011). [Pubmed] Tsai K.L, Huang C.Y, Chang C.H, Sun Y.J, Chuang W.J, Hsiao C.D. Crystal structure of the human FOXK1a-DNA complex and its implications on the diverse binding specificity of winged helix/forkhead proteins. The Journal of biological chemistry 281:17400-9 (2006). [Pubmed] Chen X, Ji Z, Webber A, Sharrocks AD. Genome-wide binding studies reveal DNA binding specificity mechanisms and functional interplay amongst Forkhead transcription factors. Nucleic Acids Res 44:1566-78 (2016). [Pubmed] Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.