DNA Binding Site

Accessions: ECK125134882 (RegulonDB 7.5)
Organisms: ECK12
Libraries: RegulonDB 7.5 1
1 Salgado H, Peralta-Gil M, Gama-Castro S, Santos-Zavaleta A, Muniz-Rascado L, Garcia-Sotelo JS, Weiss V, Solano-Lira H, Martinez-Flores I, Medina-Rivera A, Salgado-Osorio G, Alquicira-Hernandez S, Alquicira-Hernandez K, Lopez-Fuentes A, Porron-Sotelo L, Huerta AM, Bonavides-Martinez C, Balderas-Martinez YI, Pannier L, Olvera M, Labastida A, Jimenez-Jacinto V, Vega-Alvarado L, Del Moral-Chavez V, Hernandez-Alvarez A, Morett E, Collado-Vides J. RegulonDB v8.0: omics data sets, evolutionary conservation, regulatory phrases, cross-validated gold standards and more. Nucleic Acids Res. 2013 Jan 1;41(D1):D203-D213. [Pubmed]
Length: 38
Sequence: aattgatgtaACATAATCACTTACGTGAtgtgcgtgtt
Binding TFs: ECK120004808 (Bacterial regulatory proteins, lacI family, Periplasmic binding proteins and sugar binding domain of LacI family, Periplasmic binding protein-like domain, Periplasmic binding protein domain)
Binding Motifs: Cra kwGCTGAAwCGwTTmAry
Publications: Mikulskis A., Aristarkhov A., Lin EC. Regulation of expression of the ethanol dehydrogenase gene (adhE) in Escherichia coli by catabolite repressor activator protein Cra. J Bacteriol. 179(22):7129-34 (1997). [Pubmed]

Kaga N., Umitsuki G., Clark DP., Nagai K., Wachi M. Extensive overproduction of the AdhE protein by rng mutations depends on mutations in the cra gene or in the Cra-box of the adhE promoter. Biochem Biophys Res Commun. 295(1):92-7 (2002). [Pubmed]

Saier MH., Ramseier TM. The catabolite repressor/activator (Cra) protein of enteric bacteria. J Bacteriol. 178(12):3411-7 (1996). [Pubmed]

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