DNA Binding Site
| Accessions: | ACAGCTGA (UniPROBE 20160601), MA0500.3.17 (JASPAR 2024), MA1472.3.1 (JASPAR 2024), MA1593.2.1 (JASPAR 2024), MA1593.2.10 (JASPAR 2024), MA1593.2.16 (JASPAR 2024), MA1593.2.6 (JASPAR 2024), MA1593.2.9 (JASPAR 2024), MA1619.2.18 (JASPAR 2024), MA2295.1.16 (JASPAR 2024) |
| Organisms: | Caenorhabditis elegans, Homo sapiens, Mus musculus, Drosophila melanogaster |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 8 |
| Sequence: | ACAGCTGA |
| Type: | Heterodimer |
| Binding TFs: | P15173 (Helix-loop-helix DNA-binding domain, Myogenic Basic domain) UP00357A (Helix-loop-helix DNA-binding domain) UP00387A (Helix-loop-helix DNA-binding domain) Q9QYC3 (Helix-loop-helix DNA-binding domain) Q9QX98 (Helix-loop-helix DNA-binding domain) Q96PQ6 (Zinc finger, C2H2 type, KRAB box, C2H2 type zinc-finger (2 copies), Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger) P10083 P15173 Q96PQ6 Q9QX98 Q9QYC3 |
| Binding Motifs: | UP00357A_1 whyrATCAGCTGatsk UP00387A_1 ksrACAGCTGTyrwrr MA0500.3 rCAGCTGy MA1472.3 ACAGCTGT MA1593.2 ACAGCAGA MA1619.2 aCAGCTGt MA2295.1 gCAGCTGc |
| Publications: | Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed] Cao Y, Kumar R.M, Penn B.H, Berkes C.A, Kooperberg C, Boyer L.A, Young R.A, Tapscott S.J. Global and gene-specific analyses show distinct roles for Myod and Myog at a common set of promoters. The EMBO journal 25:502-11 (2006). [Pubmed] Lo HG, Jin RU, Sibbel G, Liu D, Karki A, Joens MS, Madison BB, Zhang B, Blanc V, Fitzpatrick JA, Davidson NO, Konieczny SF, Mills JC. A single transcription factor is sufficient to induce and maintain secretory cell architecture. Genes Dev 31:154-171 (2017). [Pubmed] Imbeault M, Helleboid PY, Trono D. KRAB zinc-finger proteins contribute to the evolution of gene regulatory networks. Nature 543:550-554 (2017). [Pubmed] Meredith DM, Borromeo MD, Deering TG, Casey BH, Savage TK, Mayer PR, Hoang C, Tung KC, Kumar M, Shen C, Swift GH, Macdonald RJ, Johnson JE. Program specificity for Ptf1a in pancreas versus neural tube development correlates with distinct collaborating cofactors and chromatin accessibility. Mol Cell Biol 33:3166-79 (2013). [Pubmed] Nitta KR, Jolma A, Yin Y, Morgunova E, Kivioja T, Akhtar J, Hens K, Toivonen J, Deplancke B, Furlong EE, Taipale J. Conservation of transcription factor binding specificities across 600 million years of bilateria evolution. Elife : (2015). [Pubmed] |
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