DNA Binding Site

Accessions: 1jj4_C (3D-footprint 20231221), 1jj4_D (3D-footprint 20231221), 2ayb_C (3D-footprint 20231221), 2ayb_D (3D-footprint 20231221)
Organisms: Human papillomavirus type 18, Human papillomavirus type 6a
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 16
Sequence: CAACCGAATTCGGTTG
Type: Heterodimer
Binding TFs: 1jj4_B (E2 (early) protein, C terminal)
2ayb_B (E2 (early) protein, C terminal)
Binding Motifs: 1jj4_AB CAACCGnntnCGGTTG
1jj4_B CGGTtG
2ayb_AB CAACCGnnnnCGGTTG
2ayb_B CGGTTG
Publications: Kim S.S, Tam J.K, Wang A.F, Hegde R.S. The structural basis of DNA target discrimination by papillomavirus E2 proteins. The Journal of biological chemistry 275:31245-54 (2000). [Pubmed]

Hooley E, Fairweather V, Clarke A.R, Gaston K, Brady R.L. The recognition of local DNA conformation by the human papillomavirus type 6 E2 protein. Nucleic acids research 34:3897-908 (2006). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.