DNA Binding Site

						

			
Accessions: CCACGGGG (UniPROBE 20160601), MA0104.5.15 (JASPAR 2024)

			
Organisms: Mus musculus, Homo sapiens
Libraries: UniPROBE 20160601 1, JASPAR 2024 2
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 8
Sequence: CCACGGGG
Type: Heterodimer
Binding TFs: P04198 (Helix-loop-helix DNA-binding domain, Myc amino-terminal region)
UP00057A (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
UP00102A (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
P04198
Binding Motifs: UP00057A_1 bmCCCCCgGGGGggt
UP00102A_1 smCCCCcgGGGGGg
UP00057A_2 ycdCvCAGCAkGara
UP00102A_2 ymdCrCAGCAkGmrw
MA0104.5 CCACGTGG
			
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]


Chen X, Xu H, Yuan P, Fang F, Huss M, Vega V.B, Wong E, Orlov Y.L, Zhang W, Jiang J, Loh Y.H, Yeo H.C, Yeo Z.X, Narang V, Govindarajan K.R, Leong B, Shahab A, Ruan Y, Bourque G, Sung W.K, Clarke N.D, Wei C.L, Ng H.H. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133:1106-17 (2008). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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