DNA Binding Site

						

			
Accessions: PF0015.1.1 (JASPAR 2024), PF0015.1.10 (JASPAR 2024), PF0015.1.11 (JASPAR 2024), PF0015.1.12 (JASPAR 2024), PF0015.1.13 (JASPAR 2024), PF0015.1.14 (JASPAR 2024), PF0015.1.15 (JASPAR 2024), PF0015.1.16 (JASPAR 2024), PF0015.1.17 (JASPAR 2024), PF0015.1.18 (JASPAR 2024), PF0015.1.19 (JASPAR 2024), PF0015.1.2 (JASPAR 2024), PF0015.1.20 (JASPAR 2024), PF0015.1.3 (JASPAR 2024), PF0015.1.4 (JASPAR 2024), PF0015.1.5 (JASPAR 2024), PF0015.1.6 (JASPAR 2024), PF0015.1.7 (JASPAR 2024), PF0015.1.8 (JASPAR 2024), PF0015.1.9 (JASPAR 2024), MA0521.3.1 (JASPAR 2024), MA0521.3.10 (JASPAR 2024), MA0521.3.13 (JASPAR 2024), MA0521.3.14 (JASPAR 2024), MA0521.3.15 (JASPAR 2024), MA0521.3.16 (JASPAR 2024), MA0521.3.17 (JASPAR 2024), MA0521.3.18 (JASPAR 2024), MA0521.3.2 (JASPAR 2024), MA0521.3.3 (JASPAR 2024), MA0521.3.4 (JASPAR 2024), MA0521.3.5 (JASPAR 2024), MA0521.3.6 (JASPAR 2024), MA0521.3.7 (JASPAR 2024), MA0521.3.8 (JASPAR 2024), MA0521.3.9 (JASPAR 2024), MA0633.3.1 (JASPAR 2024), MA0633.3.10 (JASPAR 2024), MA0633.3.11 (JASPAR 2024), MA0633.3.12 (JASPAR 2024), MA0633.3.13 (JASPAR 2024), MA0633.3.14 (JASPAR 2024), MA0633.3.15 (JASPAR 2024), MA0633.3.16 (JASPAR 2024), MA0633.3.19 (JASPAR 2024), MA0633.3.2 (JASPAR 2024), MA0633.3.20 (JASPAR 2024), MA0633.3.3 (JASPAR 2024), MA0633.3.4 (JASPAR 2024), MA0633.3.5 (JASPAR 2024), MA0633.3.6 (JASPAR 2024), MA0633.3.7 (JASPAR 2024), MA0633.3.8 (JASPAR 2024), MA0633.3.9 (JASPAR 2024), MA1635.2.1 (JASPAR 2024), MA1635.2.10 (JASPAR 2024), MA1635.2.11 (JASPAR 2024), MA1635.2.12 (JASPAR 2024), MA1635.2.13 (JASPAR 2024), MA1635.2.14 (JASPAR 2024), MA1635.2.15 (JASPAR 2024), MA1635.2.16 (JASPAR 2024), MA1635.2.17 (JASPAR 2024), MA1635.2.18 (JASPAR 2024), MA1635.2.19 (JASPAR 2024), MA1635.2.2 (JASPAR 2024), MA1635.2.20 (JASPAR 2024), MA1635.2.3 (JASPAR 2024), MA1635.2.4 (JASPAR 2024), MA1635.2.5 (JASPAR 2024), MA1635.2.6 (JASPAR 2024), MA1635.2.7 (JASPAR 2024), MA1635.2.8 (JASPAR 2024), MA1635.2.9 (JASPAR 2024), MA1993.2.1 (JASPAR 2024), MA1993.2.10 (JASPAR 2024), MA1993.2.11 (JASPAR 2024), MA1993.2.12 (JASPAR 2024), MA1993.2.13 (JASPAR 2024), MA1993.2.14 (JASPAR 2024), MA1993.2.15 (JASPAR 2024), MA1993.2.16 (JASPAR 2024), MA1993.2.17 (JASPAR 2024), MA1993.2.18 (JASPAR 2024), MA1993.2.19 (JASPAR 2024), MA1993.2.2 (JASPAR 2024), MA1993.2.20 (JASPAR 2024), MA1993.2.3 (JASPAR 2024), MA1993.2.4 (JASPAR 2024), MA1993.2.5 (JASPAR 2024), MA1993.2.6 (JASPAR 2024), MA1993.2.7 (JASPAR 2024), MA1993.2.8 (JASPAR 2024), MA1993.2.9 (JASPAR 2024), MA1997.2.1 (JASPAR 2024), MA1997.2.10 (JASPAR 2024), MA1997.2.11 (JASPAR 2024), MA1997.2.12 (JASPAR 2024), MA1997.2.13 (JASPAR 2024), MA1997.2.14 (JASPAR 2024), MA1997.2.15 (JASPAR 2024), MA1997.2.16 (JASPAR 2024), MA1997.2.17 (JASPAR 2024), MA1997.2.18 (JASPAR 2024), MA1997.2.2 (JASPAR 2024), MA1997.2.3 (JASPAR 2024), MA1997.2.4 (JASPAR 2024), MA1997.2.5 (JASPAR 2024), MA1997.2.6 (JASPAR 2024), MA1997.2.7 (JASPAR 2024), MA1997.2.8 (JASPAR 2024), MA1997.2.9 (JASPAR 2024), MA2308.1.1 (JASPAR 2024), MA2308.1.10 (JASPAR 2024), MA2308.1.11 (JASPAR 2024), MA2308.1.12 (JASPAR 2024), MA2308.1.13 (JASPAR 2024), MA2308.1.14 (JASPAR 2024), MA2308.1.15 (JASPAR 2024), MA2308.1.2 (JASPAR 2024), MA2308.1.9 (JASPAR 2024), MA2317.1.1 (JASPAR 2024), MA2317.1.10 (JASPAR 2024), MA2317.1.11 (JASPAR 2024), MA2317.1.12 (JASPAR 2024), MA2317.1.15 (JASPAR 2024), MA2317.1.16 (JASPAR 2024), MA2317.1.19 (JASPAR 2024), MA2317.1.2 (JASPAR 2024), MA2317.1.20 (JASPAR 2024), MA2317.1.3 (JASPAR 2024), MA2317.1.4 (JASPAR 2024), MA2317.1.5 (JASPAR 2024), MA2317.1.6 (JASPAR 2024), MA2317.1.7 (JASPAR 2024), MA2317.1.8 (JASPAR 2024), MA2317.1.9 (JASPAR 2024), MA2321.1.1 (JASPAR 2024), MA2321.1.10 (JASPAR 2024), MA2321.1.13 (JASPAR 2024), MA2321.1.14 (JASPAR 2024), MA2321.1.15 (JASPAR 2024), MA2321.1.16 (JASPAR 2024), MA2321.1.17 (JASPAR 2024), MA2321.1.18 (JASPAR 2024), MA2321.1.19 (JASPAR 2024), MA2321.1.2 (JASPAR 2024), MA2321.1.20 (JASPAR 2024), MA2321.1.3 (JASPAR 2024), MA2321.1.4 (JASPAR 2024), MA2321.1.5 (JASPAR 2024), MA2321.1.6 (JASPAR 2024), MA2321.1.7 (JASPAR 2024), MA2321.1.8 (JASPAR 2024), MA2321.1.9 (JASPAR 2024), UN0732.1.1 (JASPAR 2024), UN0732.1.10 (JASPAR 2024), UN0732.1.11 (JASPAR 2024), UN0732.1.12 (JASPAR 2024), UN0732.1.17 (JASPAR 2024), UN0732.1.18 (JASPAR 2024), UN0732.1.2 (JASPAR 2024), UN0732.1.9 (JASPAR 2024)

			
Organisms: Mus musculus, Homo sapiens, Drosophila melanogaster, Caenorhabditis elegans
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 6
Sequence: CAGCTG
Type: Heterodimer
Binding TFs: Q61286 (Helix-loop-helix DNA-binding domain)
Q13516 (Helix-loop-helix DNA-binding domain)
Q8NFJ8 (Helix-loop-helix DNA-binding domain)
Q9D030 (Helix-loop-helix DNA-binding domain)
Q62414 (Helix-loop-helix DNA-binding domain, Neuronal helix-loop-helix transcription factor )
P11420
P22816
P34555
P41894
Q13516
Q61286
Q62414
Q8NFJ8
Q9D030
Binding Motifs: PF0015.1 CAGCTG
MA0521.3 CAGCTG
MA0633.3 CAGCTG
MA1635.2 CAGCTG
MA1993.2 CAGCTG
MA1997.2 CAGCTG
MA2308.1 CAGCTG
MA2317.1 CAGCTG
MA2321.1 CAGCTG
UN0732.1 CAGCTG
			
Publications: Xie X, Lu J, Kulbokas E.J, Golub T.R, Mootha V, Lindblad-Toh K, Lander E.S, Kellis M. Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature 434:338-45 (2005). [Pubmed]


Zhang Y, Doyle K, Bina M. Interactions of HTF4 with E-box motifs in the long terminal repeat of human immunodeficiency virus type 1. Journal of virology 66:5631-4 (1992). [Pubmed]


Kophengnavong T, Michnowicz J.E, Blackwell T.K. Establishment of distinct MyoD, E2A, and twist DNA binding specificities by different basic region-DNA conformations. Molecular and cellular biology 20:261-72 (2000). [Pubmed]


Ross SE, McCord AE, Jung C, Atan D, Mok SI, Hemberg M, Kim TK, Salogiannis J, Hu L, Cohen S, Lin Y, Harrar D, McInnes RR, Greenberg ME. Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly. Neuron 73:292-303 (2012). [Pubmed]


Fong AP, Yao Z, Zhong JW, Cao Y, Ruzzo WL, Gentleman RC, Tapscott SJ. Genetic and epigenetic determinants of neurogenesis and myogenesis. Dev Cell 22:721-35 (2012). [Pubmed]


Küspert M, Hammer A, Bösl MR, Wegner M. Olig2 regulates Sox10 expression in oligodendrocyte precursors through an evolutionary conserved distal enhancer. Nucleic Acids Res 39:1280-93 (2011). [Pubmed]


Nitta KR, Jolma A, Yin Y, Morgunova E, Kivioja T, Akhtar J, Hens K, Toivonen J, Deplancke B, Furlong EE, Taipale J. Conservation of transcription factor binding specificities across 600 million years of bilateria evolution. Elife : (2015). [Pubmed]


Zhu LJ, Christensen RG, Kazemian M, Hull CJ, Enuameh MS, Basciotta MD, Brasefield JA, Zhu C, Asriyan Y, Lapointe DS, Sinha S, Wolfe SA, Brodsky MH. FlyFactorSurvey: a database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system. Nucleic Acids Res : (2011). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.