DNA Binding Site
| Accessions: | CCACGTGA (UniPROBE 20160601), MA0147.4.11 (JASPAR 2024), MA0147.4.19 (JASPAR 2024), MA0964.3.12 (JASPAR 2024), MA0964.3.20 (JASPAR 2024), MA1449.2.18 (JASPAR 2024), MA1449.2.9 (JASPAR 2024), MA2175.1.19 (JASPAR 2024), MA2175.1.8 (JASPAR 2024), MA2301.1.18 (JASPAR 2024) |
| Organisms: | Mus musculus, Saccharomyces cerevisiae, Caenorhabditis elegans, Homo sapiens, Arabidopsis thaliana, Drosophila melanogaster |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 8 |
| Sequence: | CCACGTGA |
| Type: | Heterodimer |
| Binding TFs: | P01106 (Helix-loop-helix DNA-binding domain, Myc amino-terminal region, Myc leucine zipper domain) UP00324A (Helix-loop-helix DNA-binding domain) UP00309A / UP00397A (Helix-loop-helix DNA-binding domain) UP00332A (Helix-loop-helix DNA-binding domain) UP00365A (Helix-loop-helix DNA-binding domain) UP00367A (Helix-loop-helix DNA-binding domain) UP00373A (Helix-loop-helix DNA-binding domain) UP00379A (Helix-loop-helix DNA-binding domain) UP00382A (Helix-loop-helix DNA-binding domain) UP00050A (Helix-loop-helix DNA-binding domain) UP00060A (Helix-loop-helix DNA-binding domain) Q9LEZ3 (Helix-loop-helix DNA-binding domain) H2KZZ2 (Helix-loop-helix DNA-binding domain) G5EEH5 H2KZZ2 O61735 P01106 Q9LEZ3 |
| Binding Motifs: | UP00050A_1 rrawkrgTCACGTGAsymrywy UP00060A_1 kgmsCACGTGgkcrkk UP00309A_1 kaycwgkCACGTGactbvymg UP00324A_1 gwkgmrTCACGTGAygmmbw UP00332A_1 gwcymasCACGTGsycskhw UP00365A_1 wswaTCACGTGAywawy UP00367A_1 yrdamCACGTGktymr UP00373A_1 awwAarAAACAwws UP00379A_1 ybtrvarwaaarwg UP00382A_1 Awkwwtwaaaawwa UP00397A_1 wswaywsrTCACGTGmtcdgmy UP00050A_2 ygysryTmCACGTGGArrsmrgt UP00060A_2 ktGyCAyGcGaCdk UP00373A_2 / UP00382A_2 twdasCACGTGskawb MA0147.4 CCACGTGc MA0964.3 TCACGTGA MA1449.2 TCACGTGA MA2175.1 cCACGTGg MA2301.1 tCACGTGa |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] Chen X, Xu H, Yuan P, Fang F, Huss M, Vega V.B, Wong E, Orlov Y.L, Zhang W, Jiang J, Loh Y.H, Yeo H.C, Yeo Z.X, Narang V, Govindarajan K.R, Leong B, Shahab A, Ruan Y, Bourque G, Sung W.K, Clarke N.D, Wei C.L, Ng H.H. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133:1106-17 (2008). [Pubmed] Yin Y, Vafeados D, Tao Y, Yoshida S, Asami T, Chory J. A new class of transcription factors mediates brassinosteroid-regulated gene expression in Arabidopsis. Cell 120:249-59 (2005). [Pubmed] Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed] Yuan J, Tirabassi RS, Bush AB, Cole MD. The C. elegans MDL-1 and MXL-1 proteins can functionally substitute for vertebrate MAD and MAX 17:1109-18 (Oncogene.). [Pubmed] Zhu LJ, Christensen RG, Kazemian M, Hull CJ, Enuameh MS, Basciotta MD, Brasefield JA, Zhu C, Asriyan Y, Lapointe DS, Sinha S, Wolfe SA, Brodsky MH. FlyFactorSurvey: a database of Drosophila transcription factor binding specificities determined using the bacterial one-hybrid system. Nucleic Acids Res : (2011). [Pubmed] |
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