DNA Binding Site

Accessions: CCCACCCG (UniPROBE 20160601), MA2341.1.5 (JASPAR 2024), MA2341.1.6 (JASPAR 2024)
Organisms: Saccharomyces cerevisiae, Homo sapiens
Libraries: UniPROBE 20160601 1, JASPAR 2024 2
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 8
Sequence: CCCACCCG
Type: Heterodimer
Binding TFs: UP00294A (SRF-type transcription factor (DNA-binding and dimerisation domain))
UP00599A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
UP00614D (Homeobox domain)
Q8TBJ5
Binding Motifs: UP00294A_1 tkacctwtAATTawaybwsmw
UP00599A_1 wsdymysCCCCrCCCmsyygrm
UP00614D_1 wwmwymkcAkTAATTAbcCrtmw
MA2341.1 CCCAGCCT
Publications: *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed]

Hu S, Xie Z, Onishi A, Yu X, Jiang L, Lin J, Rho HS, Woodard C, Wang H, Jeong JS, Long S, He X, Wade H, Blackshaw S, Qian J, Zhu H. Profiling the human protein-DNA interactome reveals ERK2 as a transcriptional repressor of interferon signaling. Cell 139:610-22 (2009). [Pubmed]

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