DNA Binding Site
| Accessions: | ACACGTGC (UniPROBE 20160601), MA0147.4.2 (JASPAR 2024), MA2304.1.10 (JASPAR 2024), MA2304.1.17 (JASPAR 2024), MA2304.1.20 (JASPAR 2024) |
| Organisms: | Mus musculus, Saccharomyces cerevisiae, Caenorhabditis elegans, Homo sapiens, Drosophila melanogaster |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 8 |
| Sequence: | ACACGTGC |
| Type: | Heterodimer |
| Binding TFs: | P01106 (Helix-loop-helix DNA-binding domain, Myc amino-terminal region, Myc leucine zipper domain) UP00309A / UP00397A (Helix-loop-helix DNA-binding domain) UP00332A (Helix-loop-helix DNA-binding domain) UP00367A (Helix-loop-helix DNA-binding domain) UP00370A (Helix-loop-helix DNA-binding domain) UP00373A (Helix-loop-helix DNA-binding domain) UP00382A (Helix-loop-helix DNA-binding domain) UP00383A (Helix-loop-helix DNA-binding domain) UP00050A (Helix-loop-helix DNA-binding domain) UP00060A (Helix-loop-helix DNA-binding domain) UP00548B (Helix-loop-helix DNA-binding domain) UP00548C (Helix-loop-helix DNA-binding domain) P01106 Q9VGZ5 |
| Binding Motifs: | UP00050A_1 rrawkrgTCACGTGAsymrywy UP00060A_1 kgmsCACGTGgkcrkk UP00309A_1 kaycwgkCACGTGactbvymg UP00332A_1 gwcymasCACGTGsycskhw UP00367A_1 yrdamCACGTGktymr UP00370A_1 tawgrCACGTGTchwaw UP00373A_1 awwAarAAACAwws UP00382A_1 Awkwwtwaaaawwa UP00383A_1 wmawgGCACGTGycwwa UP00397A_1 wswaywsrTCACGTGmtcdgmy UP00050A_2 ygysryTmCACGTGGArrsmrgt UP00060A_2 ktGyCAyGcGaCdk UP00373A_2 / UP00382A_2 twdasCACGTGskawb UP00548B_1 sGgamrGrCACGTGtCsyhCysy UP00548C_1 rywgggRACAGCTGtyyksracm MA0147.4 CCACGTGc MA2304.1 gCACGTGc |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] Chen X, Xu H, Yuan P, Fang F, Huss M, Vega V.B, Wong E, Orlov Y.L, Zhang W, Jiang J, Loh Y.H, Yeo H.C, Yeo Z.X, Narang V, Govindarajan K.R, Leong B, Shahab A, Ruan Y, Bourque G, Sung W.K, Clarke N.D, Wei C.L, Ng H.H. Integration of external signaling pathways with the core transcriptional network in embryonic stem cells. Cell 133:1106-17 (2008). [Pubmed] Nitta KR, Jolma A, Yin Y, Morgunova E, Kivioja T, Akhtar J, Hens K, Toivonen J, Deplancke B, Furlong EE, Taipale J. Conservation of transcription factor binding specificities across 600 million years of bilateria evolution. Elife : (2015). [Pubmed] |
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