DNA Binding Site

Accessions: 5od6_C (3D-footprint 20231221), 5od6_D (3D-footprint 20231221), 6fzs_C (3D-footprint 20231221), 6fzs_D (3D-footprint 20231221), 6fzt_C (3D-footprint 20231221), 6fzt_D (3D-footprint 20231221), 6tbz_B (3D-footprint 20231221), 6tbz_C (3D-footprint 20231221), 6zmn_C (3D-footprint 20231221), 6zmn_D (3D-footprint 20231221)
Organisms: Homo sapiens, Gallus gallus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 16
Sequence: TGCAGGCGCGCCTGCA
Type: Heterodimer
Binding TFs: 5od6_A (MH1 domain)
6fzs_B (MH1 domain)
6fzt_A (MH1 domain)
6fzt_B (MH1 domain)
6tbz_A (MH1 domain)
6zmn_B (MH1 domain)
Binding Motifs: 6fzs_B CGCCt
5od6_A CGcC
6fzs_AB aGkCGCGCCt
6fzt_A CgcC
6fzt_AB GGCGCGCC
6tbz_A CgcC
6zmn_B CGCC
Publications: Martin-Malpartida P, Batet M, Kaczmarska Z, Freier R, Gomes T, Aragón E, Zou Y, Wang Q, Xi Q, Ruiz L, Vea A, Márquez JA, Massagué J, Macias MJ. Structural basis for genome wide recognition of 5-bp GC motifs by SMAD transcription factors. Nat Commun 8:2070 (2017). [Pubmed]

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.