DNA Binding Site

Accessions: 4y5w_E (3D-footprint 20231221), 4y5w_M (3D-footprint 20231221)
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 22
Sequence: ATGGATTTCCTAGGAAGACAGA
Type: Heterodimer
Binding TFs: 4y5w_B (SH2 domain, STAT protein, all-alpha domain, STAT protein, DNA binding domain)
4y5w_C (SH2 domain, STAT protein, all-alpha domain, STAT protein, DNA binding domain)
4y5w_D (SH2 domain, STAT protein, all-alpha domain, STAT protein, DNA binding domain)
Binding Motifs: 4y5w_AC CCnnGGAAnnnnnA
4y5w_B GgAannnnnA
4y5w_BD TTCnngg
Publications: Li J, Rodriguez JP, Niu F, Pu M, Wang J, Hung LW, Shao Q, Zhu Y, Ding W, Liu Y, Da Y, Yao Z, Yang J, Zhao Y, Wei GH, Cheng G, Liu ZJ, Ouyang S. Structural basis for DNA recognition by STAT6. Proc Natl Acad Sci U S A 113:13015-13020 (2016). [Pubmed]

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