DNA Binding Site

Accessions: comC_2 (DBTBS 1.0)
Names: comC_2
Organisms: Bacillus subtilis
Libraries: DBTBS 1.0 1
1 Sierro N, Makita Y, de Hoon M, Nakai K. DBTBS: a database of transcriptional regulation in Bacillus subtilis containing upstream intergenic conservation information. Nucleic acids research 36:D93-6 (2008). [Pubmed]
Length: 30
Sequence: tcatgtgtAAAAttgaaTATTcccaattgg
Binding TFs: ComK (Basic membrane protein)
Binding Motifs: ComK_1 AAAA
ComK_2 TTTT
Publications: Hamoen L.W, Van Werkhoven A.F, Bijlsma J.J, Dubnau D, Venema G. The competence transcription factor of Bacillus subtilis recognizes short A/T-rich sequences arranged in a unique, flexible pattern along the DNA helix. Genes & development 12:1539-50 (1998). [Pubmed]

Guillen N, Weinrauch Y, Dubnau D.A. Cloning and characterization of the regulatory Bacillus subtilis competence genes comA and comB. Journal of bacteriology 171:5354-61 (1989). [Pubmed]

van Sinderen D, ten Berge A, Hayema B.J, Hamoen L, Venema G. Molecular cloning and sequence of comK, a gene required for genetic competence in Bacillus subtilis. Molecular microbiology 11:695-703 (1994). [Pubmed]

van Sinderen D, Luttinger A, Kong L, Dubnau D, Venema G, Hamoen L. comK encodes the competence transcription factor, the key regulatory protein for competence development in Bacillus subtilis. Molecular microbiology 15:455-62 (1995). [Pubmed]

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