DNA Binding Site

Accessions: 1egw_F (3D-footprint 20231221), 3mu6_F (3D-footprint 20231221)
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 16
Sequence: AAGCTAATAATAGCTT
Type: Heterodimer
Binding TFs: 1egw_B (SRF-type transcription factor (DNA-binding and dimerisation domain))
3mu6_B (SRF-type transcription factor (DNA-binding and dimerisation domain))
Binding Motifs: 1egw_AB CTannnnTAg
3mu6_AB CTAnnnnTAG
Publications: Santelli E, Richmond T.J. Crystal structure of MEF2A core bound to DNA at 1.5 A resolution. Journal of molecular biology 297:437-49 (2000). [Pubmed]

Jayathilaka N, Han A, Gaffney K.J, Dey R, Jarusiewicz J.A, Noridomi K, Philips M.A, Lei X, He J, Ye J, Gao T, Petasis N.A, Chen L. Inhibition of the function of class IIa HDACs by blocking their interaction with MEF2. Nucleic acids research 40:5378-88 (2012). [Pubmed]

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