DNA Binding Site

Accessions: MA0157.4.4 (JASPAR 2024), MA0480.3.9 (JASPAR 2024), MA0852.3.3 (JASPAR 2024), MA1103.3.19 (JASPAR 2024), MA1606.2.6 (JASPAR 2024)
Organisms: Mus musculus, Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 7
Sequence: GTAAAGA
Type: Heterodimer
Binding TFs: Q9WVH4 (Fork head domain)
Q9R1E0 (Fork head domain)
Q01167 (Fork head domain, FHA domain)
Q61080 (Fork head domain)
P85037 (Fork head domain, FHA domain)
P85037
Q01167
Q61080
Q9R1E0
Q9WVH4
Binding Motifs: MA0157.4 GTAAACA
MA0480.3 GTAAACA
MA0852.3 GTAAACA
MA1103.3 GTAAACA
MA1606.2 rTAAACA
Publications: Portales-Casamar E, Kirov S, Lim J, Lithwick S, Swanson M.I, Ticoll A, Snoddy J, Wasserman W.W. PAZAR: a framework for collection and dissemination of cis-regulatory sequence annotation. Genome biology 8:R207 (2007). [Pubmed]

Furuyama T., Nakazawa T., Nakano I., Mori N. Identification of the differential distribution patterns of mRNAs and consensus binding sequences for mouse DAF-16 homologues. Biochem. J. 349:629-634 (2000). [Pubmed]

Tsai K.L, Huang C.Y, Chang C.H, Sun Y.J, Chuang W.J, Hsiao C.D. Crystal structure of the human FOXK1a-DNA complex and its implications on the diverse binding specificity of winged helix/forkhead proteins. The Journal of biological chemistry 281:17400-9 (2006). [Pubmed]

Chen X, Ji Z, Webber A, Sharrocks AD. Genome-wide binding studies reveal DNA binding specificity mechanisms and functional interplay amongst Forkhead transcription factors. Nucleic Acids Res 44:1566-78 (2016). [Pubmed]

Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.