DNA Binding Site

Accessions: purA_1 (DBTBS 1.0)
Names: purA_1
Organisms: Bacillus subtilis
Libraries: DBTBS 1.0 1
1 Sierro N, Makita Y, de Hoon M, Nakai K. DBTBS: a database of transcriptional regulation in Bacillus subtilis containing upstream intergenic conservation information. Nucleic acids research 36:D93-6 (2008). [Pubmed]
Length: 54
Sequence: gaatGGAAGCGAACGAATatagatttacaataaatTAATGTTCGGATTTacaat
Binding TFs: PurR (Phosphoribosyl transferase domain, Bacterial purine repressor, N-terminal)
Binding Motifs: PurR AAWwmCGAAyrwTa
Publications: Saxild H.H, Brunstedt K, Nielsen K.I, Jarmer H, Nygaard P. Definition of the Bacillus subtilis PurR operator using genetic and bioinformatic tools and expansion of the PurR regulon with glyA, guaC, pbuG, xpt-pbuX, yqhZ-folD, and pbuO. Journal of bacteriology 183:6175-83 (2001). [Pubmed]

Saxild H.H, Nygaard P. Regulation of levels of purine biosynthetic enzymes in Bacillus subtilis: effects of changing purine nucleotide pools. Journal of general microbiology 137:2387-94 (1991). [Pubmed]

Weng M, Nagy P.L, Zalkin H. Identification of the Bacillus subtilis pur operon repressor. Proceedings of the National Academy of Sciences of the United States of America 92:7455-9 (1995). [Pubmed]

Shin B.S, Stein A, Zalkin H. Interaction of Bacillus subtilis purine repressor with DNA. Journal of bacteriology 179:7394-402 (1997). [Pubmed]

Rappu P, Shin B.S, Zalkin H, Mäntsälä P. A role for a highly conserved protein of unknown function in regulation of Bacillus subtilis purA by the purine repressor. Journal of bacteriology 181:3810-5 (1999). [Pubmed]

Rappu P, Leppihalme M, Mäntsälä P. Mutational analysis of the Bacillus subtilis purA operator site. Current microbiology 51:322-6 (2005). [Pubmed]

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