DNA Binding Site

Accessions: ATGCTAAT (UniPROBE 20160601)
Organisms: Mus musculus, Homo sapiens
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 8
Sequence: ATGCTAAT
Type: Heterodimer
Binding TFs: UP00179A (Homeobox domain, Pou domain - N-terminal to homeobox domain)
UP00630A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
UP00630B (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
UP00630C (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
Binding Motifs: UP00179A_1 ttkTATGCWAATkara
UP00630A_1 ywmakrtATGCTAAyttwgmmr
UP00630A_2 ywhwkrtATGCTAAyywwgmmv
UP00630B_1 twhrkdtATGCTAAyywwkmmr
UP00630B_2 ywhdddtATGCTAAytwwkhmv
UP00630C_1 bwmwkrtATGCTAAytwwghmv
UP00630C_2 ydmdgrtATGCTAAytwwgmmv
Publications: Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed]

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