DNA Binding Site
| Accessions: | ACACGTGT (UniPROBE 20160601), MA1641.2.1 (JASPAR 2024), MA1641.2.2 (JASPAR 2024) |
| Organisms: | Mus musculus, Saccharomyces cerevisiae, Caenorhabditis elegans, Homo sapiens |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 8 |
| Sequence: | ACACGTGT |
| Type: | Heterodimer |
| Binding TFs: | UP00036A (Helix-loop-helix DNA-binding domain, Myogenic Basic domain) UP00236A (Homeobox domain, Homeobox KN domain) UP00309A / UP00397A (Helix-loop-helix DNA-binding domain) UP00332A (Helix-loop-helix DNA-binding domain) UP00364A (Helix-loop-helix DNA-binding domain) UP00367A (Helix-loop-helix DNA-binding domain) UP00370A (Helix-loop-helix DNA-binding domain) UP00383A (Helix-loop-helix DNA-binding domain) UP00457A (Basic region leucine zipper) UP00060A (Helix-loop-helix DNA-binding domain) UP00548B (Helix-loop-helix DNA-binding domain) UP00548C (Helix-loop-helix DNA-binding domain) P13349 (Helix-loop-helix DNA-binding domain, Myogenic Basic domain, Myogenic determination factor 5) P13349 |
| Binding Motifs: | UP00036A_1 rrrgrACAGbTGtyyg UP00060A_1 kgmsCACGTGgkcrkk UP00236A_1 wwdrTACATGTAarwkw UP00309A_1 kaycwgkCACGTGactbvymg UP00332A_1 gwcymasCACGTGsycskhw UP00364A_1 rkrCgCGTGTCCcwd UP00367A_1 yrdamCACGTGktymr UP00370A_1 tawgrCACGTGTchwaw UP00383A_1 wmawgGCACGTGycwwa UP00397A_1 wswaywsrTCACGTGmtcdgmy UP00036A_2 vsmrmCAgmCgcrcc UP00060A_2 ktGyCAyGcGaCdk UP00457A_1 srkggGgACACGTGTymasawc UP00548B_1 sGgamrGrCACGTGtCsyhCysy UP00548C_1 rywgggRACAGCTGtyyksracm MA1641.2 aCAGCTGt |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] Conerly ML, Yao Z, Zhong JW, Groudine M, Tapscott SJ. Distinct Activities of Myf5 and MyoD Indicate Separate Roles in Skeletal Muscle Lineage Specification and Differentiation. Dev Cell 36:375-85 (2016). [Pubmed] |
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