DNA Binding Site
| Accessions: | ACACGTGG (UniPROBE 20160601), MA2170.1.11 (JASPAR 2024), MA2175.1.12 (JASPAR 2024), MA2176.1.11 (JASPAR 2024), MA2176.1.6 (JASPAR 2024), UN0803.1.11 (JASPAR 2024) |
| Organisms: | Mus musculus, Saccharomyces cerevisiae, Caenorhabditis elegans, Homo sapiens |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 8 |
| Sequence: | ACACGTGG |
| Type: | Heterodimer |
| Binding TFs: | UP00397A (Helix-loop-helix DNA-binding domain) UP00332A (Helix-loop-helix DNA-binding domain) UP00367A (Helix-loop-helix DNA-binding domain) UP00373A (Helix-loop-helix DNA-binding domain) UP00382A (Helix-loop-helix DNA-binding domain) UP00383A (Helix-loop-helix DNA-binding domain) Q18711 (Helix-loop-helix DNA-binding domain) UP00457A (Basic region leucine zipper) UP00060A (Helix-loop-helix DNA-binding domain) UP00548B (Helix-loop-helix DNA-binding domain) G5EEH5 Q10574 Q14582 Q18711 |
| Binding Motifs: | UP00060A_1 kgmsCACGTGgkcrkk UP00332A_1 gwcymasCACGTGsycskhw UP00367A_1 yrdamCACGTGktymr UP00373A_1 awwAarAAACAwws UP00382A_1 Awkwwtwaaaawwa UP00383A_1 wmawgGCACGTGycwwa UP00397A_1 wswaywsrTCACGTGmtcdgmy UP00060A_2 ktGyCAyGcGaCdk UP00373A_2 / UP00382A_2 twdasCACGTGskawb UP00457A_1 srkggGgACACGTGTymasawc UP00548B_1 sGgamrGrCACGTGtCsyhCysy MA2170.1 ACAGrTGk MA2175.1 cCACGTGg MA2176.1 cCACGTGg UN0803.1 CCACGTGG |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] Portman DS, Emmons SW. The basic helix-loop-helix transcription factors LIN-32 and HLH-2 function together in multiple steps of a C. elegans neuronal sublineage 127:5415-26 (Development.). [Pubmed] Yuan J, Tirabassi RS, Bush AB, Cole MD. The C. elegans MDL-1 and MXL-1 proteins can functionally substitute for vertebrate MAD and MAX 17:1109-18 (Oncogene.). [Pubmed] Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed] |
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