DNA Binding Site
| Accessions: | comGA_2 (DBTBS 1.0) |
| Names: | comGA_2 |
| Organisms: | Bacillus subtilis |
| Libraries: | DBTBS 1.0 1 1 Sierro N, Makita Y, de Hoon M, Nakai K. DBTBS: a database of transcriptional regulation in Bacillus subtilis containing upstream intergenic conservation information. Nucleic acids research 36:D93-6 (2008). [Pubmed] |
| Length: | 38 |
| Sequence: | atataacatctcacAAAAtcacgTTTTccctgtttgat |
| Binding TFs: | ComK (Basic membrane protein) |
| Binding Motifs: | ComK_1 AAAA ComK_2 TTTT |
| Publications: | Hamoen L.W, Van Werkhoven A.F, Bijlsma J.J, Dubnau D, Venema G. The competence transcription factor of Bacillus subtilis recognizes short A/T-rich sequences arranged in a unique, flexible pattern along the DNA helix. Genes & development 12:1539-50 (1998). [Pubmed] Guillen N, Weinrauch Y, Dubnau D.A. Cloning and characterization of the regulatory Bacillus subtilis competence genes comA and comB. Journal of bacteriology 171:5354-61 (1989). [Pubmed] van Sinderen D, ten Berge A, Hayema B.J, Hamoen L, Venema G. Molecular cloning and sequence of comK, a gene required for genetic competence in Bacillus subtilis. Molecular microbiology 11:695-703 (1994). [Pubmed] van Sinderen D, Luttinger A, Kong L, Dubnau D, Venema G, Hamoen L. comK encodes the competence transcription factor, the key regulatory protein for competence development in Bacillus subtilis. Molecular microbiology 15:455-62 (1995). [Pubmed] Roggiani M, Hahn J, Dubnau D. Suppression of early competence mutations in Bacillus subtilis by mec mutations. Journal of bacteriology 172:4056-63 (1990). [Pubmed] Kong L, Siranosian K.J, Grossman A.D, Dubnau D. Sequence and properties of mecA, a negative regulator of genetic competence in Bacillus subtilis. Molecular microbiology 9:365-73 (1993). [Pubmed] Kong L, Dubnau D. Regulation of competence-specific gene expression by Mec-mediated protein-protein interaction in Bacillus subtilis. Proceedings of the National Academy of Sciences of the United States of America 91:5793-7 (1994). [Pubmed] Hahn J, Luttinger A, Dubnau D. Regulatory inputs for the synthesis of ComK, the competence transcription factor of Bacillus subtilis. Molecular microbiology 21:763-75 (1996). [Pubmed] Berka R.M, Hahn J, Albano M, Draskovic I, Persuh M, Cui X, Sloma A, Widner W, Dubnau D. Microarray analysis of the Bacillus subtilis K-state: genome-wide expression changes dependent on ComK. Molecular microbiology 43:1331-45 (2002). [Pubmed] |
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