DNA Binding Site

Accessions: 4xic_B (3D-footprint 20231221), 5jlw_E (3D-footprint 20231221), 5jlx_B (3D-footprint 20231221)
Organisms: Drosophila melanogaster
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 14
Sequence: AGAAAGCATTAGAG
Type: Heterodimer
Binding TFs: 4xic_A (Homeobox domain)
5jlw_D / 5jlx_A (Homeobox domain)
Binding Motifs: 4xic_A CTAAtg
5jlw_D CATTAG
5jlx_A GCATTAG
Publications: Zandarashvili L, Nguyen D, Anderson KM, White MA, Gorenstein DG, Iwahara J. Entropic Enhancement of Protein-DNA Affinity by Oxygen-to-Sulfur Substitution in DNA Phosphate. Biophys J 109:1026-37 (2015). [Pubmed]

Nguyen D, Zandarashvili L, White MA, Iwahara J. Stereospecific Effects of Oxygen-to-Sulfur Substitution in DNA Phosphate on Ion Pair Dynamics and Protein-DNA Affinity. Chembiochem 17:1636-42 (2016). [Pubmed]

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