DNA Binding Site

Accessions: 6df5_D (3D-footprint 20231221), 6df8_D (3D-footprint 20231221), 6dfa_D (3D-footprint 20231221), 6dfb_D (3D-footprint 20231221)
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 18
Sequence: TGCTTCCTGCCAATAACG
Type: Heterodimer
Binding TFs: 6df5_A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
6df8_A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
6dfa_A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
6dfb_A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Binding Motifs: 6df5_A tGGCAGGa
6df8_A TGGCAGGA
6dfa_A TGGCAGGA
6dfb_A TCCTGCCA
Publications: Nikolova EN, Stanfield RL, Dyson HJ, Wright PE. A Conformational Switch in the Zinc Finger Protein Kaiso Mediates Differential Readout of Specific and Methylated DNA Sequences. Biochemistry 59:1909-1926 (2020). [Pubmed]

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