DNA Binding Site

Accessions: MA0499.2.16 (JASPAR 2024), MA0830.2.11 (JASPAR 2024), MA0830.2.6 (JASPAR 2024), MA1631.1.11 (JASPAR 2024), MA1631.1.7 (JASPAR 2024)
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 13
Sequence: CGGCAGCTGTCGT
Type: Heterodimer
Binding TFs: P15884 (Helix-loop-helix DNA-binding domain)
P15172 (Helix-loop-helix DNA-binding domain, Myogenic Basic domain, Myogenic determination factor 5)
P50553 (Helix-loop-helix DNA-binding domain)
P15172
P15884
P50553
Binding Motifs: MA0499.2 cwgCACCTGTymy
MA0830.2 cggCACCTGccss
MA1631.1 cdgCACCTGCysc
Publications: Cao Y, Yao Z, Sarkar D, Lawrence M, Sanchez G.J, Parker M.H, MacQuarrie K.L, Davison J, Morgan M.T, Ruzzo W.L, Gentleman R.C, Tapscott S.J. Genome-wide MyoD binding in skeletal muscle cells: a potential for broad cellular reprogramming. Developmental cell 18:662-74 (2010). [Pubmed]

Yang J, Horton JR, Li J, Huang Y, Zhang X, Blumenthal RM, Cheng X. Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine. Nucleic Acids Res 47:8375-8387 (2019). [Pubmed]

Aydin B, Kakumanu A, Rossillo M, Moreno-Estellés M, Garipler G, Ringstad N, Flames N, Mahony S, Mazzoni EO. Proneural factors Ascl1 and Neurog2 contribute to neuronal subtype identities by establishing distinct chromatin landscapes. Nat Neurosci 22:897-908 (2019). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.