DNA Binding Site
| Accessions: | MA0499.2.16 (JASPAR 2024), MA0830.2.11 (JASPAR 2024), MA0830.2.6 (JASPAR 2024), MA1631.1.11 (JASPAR 2024), MA1631.1.7 (JASPAR 2024) |
| Organisms: | Homo sapiens |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 13 |
| Sequence: | CGGCAGCTGTCGT |
| Type: | Heterodimer |
| Binding TFs: | P15884 (Helix-loop-helix DNA-binding domain) P15172 (Helix-loop-helix DNA-binding domain, Myogenic Basic domain, Myogenic determination factor 5) P50553 (Helix-loop-helix DNA-binding domain) P15172 P15884 P50553 |
| Binding Motifs: | MA0499.2 cwgCACCTGTymy MA0830.2 cggCACCTGccss MA1631.1 cdgCACCTGCysc |
| Publications: | Cao Y, Yao Z, Sarkar D, Lawrence M, Sanchez G.J, Parker M.H, MacQuarrie K.L, Davison J, Morgan M.T, Ruzzo W.L, Gentleman R.C, Tapscott S.J. Genome-wide MyoD binding in skeletal muscle cells: a potential for broad cellular reprogramming. Developmental cell 18:662-74 (2010). [Pubmed] Yang J, Horton JR, Li J, Huang Y, Zhang X, Blumenthal RM, Cheng X. Structural basis for preferential binding of human TCF4 to DNA containing 5-carboxylcytosine. Nucleic Acids Res 47:8375-8387 (2019). [Pubmed] Aydin B, Kakumanu A, Rossillo M, Moreno-Estellés M, Garipler G, Ringstad N, Flames N, Mahony S, Mazzoni EO. Proneural factors Ascl1 and Neurog2 contribute to neuronal subtype identities by establishing distinct chromatin landscapes. Nat Neurosci 22:897-908 (2019). [Pubmed] |
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