DNA Binding Site

Accessions: comK_4 (DBTBS 1.0)
Names: comK_4
Organisms: Bacillus subtilis
Libraries: DBTBS 1.0 1
1 Sierro N, Makita Y, de Hoon M, Nakai K. DBTBS: a database of transcriptional regulation in Bacillus subtilis containing upstream intergenic conservation information. Nucleic acids research 36:D93-6 (2008). [Pubmed]
Length: 29
Sequence: accattaaatatcattAAAAgatgaTTTT
Binding TFs: ComK (Basic membrane protein)
Binding Motifs: ComK_1 AAAA
ComK_2 TTTT
Publications: Hamoen L.W, Van Werkhoven A.F, Bijlsma J.J, Dubnau D, Venema G. The competence transcription factor of Bacillus subtilis recognizes short A/T-rich sequences arranged in a unique, flexible pattern along the DNA helix. Genes & development 12:1539-50 (1998). [Pubmed]

van Sinderen D, Luttinger A, Kong L, Dubnau D, Venema G, Hamoen L. comK encodes the competence transcription factor, the key regulatory protein for competence development in Bacillus subtilis. Molecular microbiology 15:455-62 (1995). [Pubmed]

Berka R.M, Hahn J, Albano M, Draskovic I, Persuh M, Cui X, Sloma A, Widner W, Dubnau D. Microarray analysis of the Bacillus subtilis K-state: genome-wide expression changes dependent on ComK. Molecular microbiology 43:1331-45 (2002). [Pubmed]

van Sinderen D, Venema G. comK acts as an autoregulatory control switch in the signal transduction route to competence in Bacillus subtilis. Journal of bacteriology 176:5762-70 (1994). [Pubmed]

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