DNA Binding Site

Accessions: 1qp9_F (3D-footprint 20231221), 2hap_B (3D-footprint 20231221)
Organisms: Saccharomyces cerevisiae
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 20
Sequence: ACTAATAGCGATAATAGCGT
Type: Heterodimer
Binding TFs: 1qp9_B (Fungal Zn(2)-Cys(6) binuclear cluster domain)
2hap_D (Fungal Zn(2)-Cys(6) binuclear cluster domain)
Binding Motifs: 1qp9_AB CGCnnnTATCGCnnnTAG
1qp9_B ATAnnnGCG
2hap_CD CGCtntTATCGC
2hap_D ATAAnaGCG
Publications: Lukens A.K, King D.A, Marmorstein R. Structure of HAP1-PC7 bound to DNA: implications for DNA recognition and allosteric effects of DNA-binding on transcriptional activation. Nucleic acids research 28:3853-63 (2000). [Pubmed]

King D.A, Zhang L, Guarente L, Marmorstein R. Structure of HAP1-18-DNA implicates direct allosteric effect of protein-DNA interactions on transcriptional activation. Nature structural biology 6:22-7 (1999). [Pubmed]

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