DNA Binding Site

						

			
Accessions: MA0039.4.8 (JASPAR 2024), UN0334.1.1 (JASPAR 2024), MA1728.1.1 (JASPAR 2024)

			
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 12
Sequence: ACCGCCGCCCGG
Type: Heterodimer
Binding TFs: O43474 (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Q6P9A3 (Zinc finger, C2H2 type, KRAB box, Zinc-finger double domain, C2H2-type zinc finger, C2H2-type zinc finger)
O43474
Q6P9A3
Binding Motifs: MA0039.4 ssCCCCACCChs
MA1728.1 / UN0334.1 rsTGCTGCCCwr
			
Publications: Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]


Schmitges FW, Radovani E, Najafabadi HS, Barazandeh M, Campitelli LF, Yin Y, Jolma A, Zhong G, Guo H, Kanagalingam T, Dai WF, Taipale J, Emili A, Greenblatt JF, Hughes TR. Multiparameter functional diversity of human C2H2 zinc finger proteins. Genome Res 26:1742-1752 (2016). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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