DNA Binding Site
| Accessions: | CCACGCAC (UniPROBE 20160601), MA1645.2.2 (JASPAR 2024), MA1650.2.11 (JASPAR 2024) |
| Organisms: | Eremothecium gossypii, Kluyveromyces lactis, Homo sapiens |
| Libraries: | UniPROBE 20160601 1, JASPAR 2024 2 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 8 |
| Sequence: | CCACGCAC |
| Type: | Heterodimer |
| Binding TFs: | O95096 (Homeobox domain) O43829 (Zinc finger, C2H2 type, BTB/POZ domain, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger) UP00516A (Fork head domain) UP00524A (Fork head domain) UP00587B (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger) UP00587D (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger) O43829 O95096 |
| Binding Motifs: | UP00516A_1 cmmsgrgyGACGCAAAhsgwmrv UP00516A_2 mhrmsyacrktGcgyGsktkay UP00524A_1 tsctdrarysACGCAAwhrvcyy UP00524A_2 ydydgkggCGCGCGTcrtmhtms UP00587B_1 aacysaaAACACGCAwwyhywm UP00587D_1 ktstwmyCCCMCGCAhtwtyaw MA1645.2 CCACTCAA MA1650.2 CCGCGCAC |
| Publications: | Nakagawa S, Gisselbrecht SS, Rogers JM, Hartl DL, Bulyk ML. DNA-binding specificity changes in the evolution of forkhead transcription factors. Proc Natl Acad Sci U S A 110:12349-54 (2013). [Pubmed] Berger M.F, Badis G, Gehrke A.R, Talukder S, Philippakis A.A, Peña-Castillo L, Alleyne T.M, Mnaimneh S, Botvinnik O.B, Chan E.T, Khalid F, Zhang W, Newburger D, Jaeger S.A, Morris Q.D, Bulyk M.L, Hughes T.R. Variation in homeodomain DNA binding revealed by high-resolution analysis of sequence preferences. Cell 133:1266-76 (2008). [Pubmed] Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
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