DNA Binding Site

Accessions: 6fqp_L (3D-footprint 20231221), 6fqp_M (3D-footprint 20231221), 6fqq_G (3D-footprint 20231221), 6fqq_H (3D-footprint 20231221), 6fqq_L (3D-footprint 20231221), 6fqq_M (3D-footprint 20231221)
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 16
Type: Heterodimer
Binding TFs: 6fqp_B (Homeobox domain, Homeobox KN domain)
6fqq_B / 6fqq_E (Homeobox domain, Homeobox KN domain)
Binding Motifs: 6fqp_AB TGACAgCtGTCA
6fqp_B ctGTCA
6fqq_E tGACAg
Publications: Guca E, Suñol D, Ruiz L, Konkol A, Cordero J, Torner C, Aragon E, Martin-Malpartida P, Riera A, Macias MJ. TGIF1 homeodomain interacts with Smad MH1 domain and represses TGF-β signaling. Nucleic Acids Res 46:9220-9235 (2018). [Pubmed]

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.