DNA Binding Site

						

			
Accessions: AATCGATT (UniPROBE 20160601), MA2102.1.1 (JASPAR 2024), MA2102.1.2 (JASPAR 2024)

			
Organisms: Homo sapiens
Libraries: UniPROBE 20160601 1, JASPAR 2024 2
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 8
Sequence: AATCGATT
Type: Heterodimer
Binding TFs: UP00609A (Homeobox domain, 'Paired box' domain, Homeobox KN domain)
UP00609B (Homeobox domain, 'Paired box' domain, Homeobox KN domain)
UP00609C (Homeobox domain, 'Paired box' domain, Homeobox KN domain)
UP00609D (Homeobox domain, 'Paired box' domain, Homeobox KN domain)
UP00609E (Homeobox domain, 'Paired box' domain, Homeobox KN domain)
UP00609G (Homeobox domain, 'Paired box' domain, Homeobox KN domain)
UP00609H (Homeobox domain, 'Paired box' domain, Homeobox KN domain)
UP00624A (Homeobox domain)
Q13105
Binding Motifs: UP00609A_1 ctmwrkTAATCGATTAdckwtc
UP00609B_1 kawmktTAATCGATTAmyrrad
UP00609C_1 krwmktTAATCGATTActrgmd
UP00609D_1 katckwTAATCGATTAmyrsak
UP00609E_1 kawmktTAATCGATTActrgad
UP00609G_1 kawmkyTAATCGATTAmyrkmd
UP00609H_1 kawmktTAATCGATTAcyksad
UP00624A_1 wwmdwkgbTAATTAkcmawwawa
MA2102.1 AATCGATT
			
Publications: Barrera LA, Vedenko A, Kurland JV, Rogers JM, Gisselbrecht SS, Rossin EJ, Woodard J, Mariani L, Kock KH, Inukai S, Siggers T, Shokri L, Gordân R, Sahni N, Cotsapas C, Hao T, Yi S, Kellis M, Daly MJ, Vidal M, Hill DE, Bulyk ML. Survey of variation in human transcription factors reveals prevalent DNA binding changes. Science 351:1450-4 (2016). [Pubmed]


Barrilleaux BL, Burow D, Lockwood SH, Yu A, Segal DJ, Knoepfler PS. Miz-1 activates gene expression via a novel consensus DNA binding motif. PLoS One : (2014). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.