DNA Binding Site

Accessions: CACATTAC (UniPROBE 20160601)
Organisms: Homo sapiens
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Length: 8
Sequence: CACATTAC
Type: Heterodimer
Binding TFs: UP00584B (Homeobox domain)
UP00584D (Homeobox domain)
UP00599C (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
UP00599D (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
UP00609F (Homeobox domain, 'Paired box' domain, Homeobox KN domain)
Binding Motifs: UP00584B_1 wcywgmvaysayATGTactarms
UP00584D_2 smysmwatrtryayatrkAwkwd
UP00599C_2 wwhywmcCCGCCCmmCcrbksws
UP00599D_2 wkhwasaCACATwaCAkwaakyk
UP00609F_1 wwkykktAyawyayAtarrgkkc
Publications: Barrera LA, Vedenko A, Kurland JV, Rogers JM, Gisselbrecht SS, Rossin EJ, Woodard J, Mariani L, Kock KH, Inukai S, Siggers T, Shokri L, Gordân R, Sahni N, Cotsapas C, Hao T, Yi S, Kellis M, Daly MJ, Vidal M, Hill DE, Bulyk ML. Survey of variation in human transcription factors reveals prevalent DNA binding changes. Science 351:1450-4 (2016). [Pubmed]

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