DNA Binding Site

Accessions: MA0764.2.16 (JASPAR 2024), MA0764.2.17 (JASPAR 2024), MA0764.2.19 (JASPAR 2024), MA0474.4.16 (JASPAR 2024), MA2340.1.11 (JASPAR 2024), MA2340.1.2 (JASPAR 2024), MA2340.1.4 (JASPAR 2024)
Organisms: Homo sapiens, Mus musculus
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 10
Sequence: ACAGGAAGTG
Type: Heterodimer
Binding TFs: P81270 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
P43268 (Ets-domain, PEA3 subfamily ETS-domain transcription factor N terminal domain)
P43268
P81270
Q3V1Q5
Binding Motifs: MA0764.2 rcAGGAAGyr
MA0474.4 aCAGGAAGTg
MA2340.1 ACCGGAAGtG
Publications: Cooper C.D, Newman J.A, Aitkenhead H, Allerston C.K, Gileadi O. Structures of the Ets Domains of Transcription Factors ETV1, ETV4, ETV5 and FEV: Determinants of DNA Binding and Redox Regulation by Disulfide bond formation. The Journal of biological chemistry : (2015). [Pubmed]

Wei G-H, Badis G, Berger MF, Kivioja T, Palin K, Enge M, Bonke M, Jolma A, Varjosalo M, Gehrke AR, Yan J, Talukder S, Turunen M, Taipale M, Stunnenberg HG, Ukkonen E, Hughes TR, Bulyk ML, Taipale J. Genome-wide analysis of ETS family DNA-binding in vitro and in vivo. The EMBO Journal. Epub 2010 Jun 1. doi:10.1038/emboj.2010.106 [Pubmed]

Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]

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