DNA Binding Site
| Accessions: | 1ahd_B (3D-footprint 20231221), 4xic_C (3D-footprint 20231221), 4xid_C (3D-footprint 20231221), 5jlw_F (3D-footprint 20231221), 5jlx_C (3D-footprint 20231221), 9ant_F (3D-footprint 20231221) |
| Organisms: | Drosophila melanogaster, Drosophila subobscura |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Length: | 14 |
| Sequence: | CTCTAATGGCTTTC |
| Type: | Heterodimer |
| Binding TFs: | 1ahd_P (Homeobox domain) 9ant_B (Homeobox domain) 4xic_A (Homeobox domain) 4xid_A (Homeobox domain) 5jlw_D / 5jlx_A (Homeobox domain) |
| Binding Motifs: | 1ahd_P AnnnCATtAGA 4xic_A CTAAtg 4xid_A CcaTTAG 5jlw_D CATTAG 5jlx_A GCATTAG 9ant_B CTAATAG |
| Publications: | Billeter M., Qian Y.-Q., Otting G., Mulller M., Gehring W. J., Wutethrich K. Determination of the nuclear magnetic resonance solution structure of an Antennapedia homeodomain-DNA complex. J. Mol. Biol. 234:1084-1093 (1993). [Pubmed] Zandarashvili L, Nguyen D, Anderson KM, White MA, Gorenstein DG, Iwahara J. Entropic Enhancement of Protein-DNA Affinity by Oxygen-to-Sulfur Substitution in DNA Phosphate. Biophys J 109:1026-37 (2015). [Pubmed] Nguyen D, Zandarashvili L, White MA, Iwahara J. Stereospecific Effects of Oxygen-to-Sulfur Substitution in DNA Phosphate on Ion Pair Dynamics and Protein-DNA Affinity. Chembiochem 17:1636-42 (2016). [Pubmed] Fraenkel E, Pabo C.O. Comparison of X-ray and NMR structures for the Antennapedia homeodomain-DNA complex. Nature structural biology 5:692-7 (1998). [Pubmed] |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.