DNA Binding Site
| Accessions: | 6vvy_O (3D-footprint 20231221) |
| Organisms: | Mycobacterium tuberculosis, strain ATCC 25618 / H37Rv |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Length: | 64 |
| Sequence: | CGAACCTGGTCTTGACTCCATTGCCGGATTTGTATTAGACTGGCAGGGTTGCCCCGAAGC GGGC |
| Type: | Heterodimer |
| Binding TFs: | 6vvy_F (Sigma-70 factor, region 1.2, Sigma-70 region 3, Sigma-70 region 2 , Sigma-70, region 4) 6vvy_M (CarD-like/TRCF domain) |
| Binding Motifs: | 6vvy_CDFJM AACnCTGCCAGTCTAAnnnAnnnnnnnnnnnnnnGTCAAGA 6vvy_F TCTTGACnnnnnnnnnnnnnnTnnnTTAGnCTGGCA |
| Publications: | Lilic M, Chen J, Boyaci H, Braffman N, Hubin EA, Herrmann J, Müller R, Mooney R, Landick R, Darst SA, Campbell EA. The antibiotic sorangicin A inhibits promoter DNA unwinding in a Mycobacterium tuberculosis rifampicin-resistant RNA polymerase. Proc Natl Acad Sci U S A 117:30423-30432 (2020). [Pubmed] |
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