DNA Binding Site

						

			
Accessions: 4r2a_C (3D-footprint 20231221), 4r2c_C (3D-footprint 20231221), 4r2d_C (3D-footprint 20231221), 4r2e_C (3D-footprint 20231221), 4r2p_C (3D-footprint 20231221), 4r2q_C (3D-footprint 20231221), 4r2r_C (3D-footprint 20231221), 5kl4_F (3D-footprint 20231221), 5kl5_C (3D-footprint 20231221), 5kl7_C (3D-footprint 20231221)

			
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Length: 9
Sequence: AGCCCACGC
Type: Heterodimer
Binding TFs: 4r2d_A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
4r2a_A / 4r2c_A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
4r2e_A (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
4r2p_A (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
4r2q_A / 4r2r_A (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
5kl4_D (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
5kl5_A (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
5kl7_A (Zinc finger, C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Binding Motifs: 4r2a_A GCGTGGGcg
4r2c_A GCGTGGGGt
4r2d_A AGCCCACGC
4r2e_A GCGTGGGcGG
4r2p_A gCGTGGGGt
4r2q_A aGCCCACGC
4r2r_A AGCCCACGC
5kl4_D aGCCCACGc
5kl5_A GCGTGGGgt
5kl7_A AGCCCACGC
			
Publications: Hashimoto H, Olanrewaju Y.O, Zheng Y, Wilson G.G, Zhang X, Cheng X. Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence. Genes & development 28:2304-13 (2014). [Pubmed]


Hashimoto H, Zhang X, Zheng Y, Wilson GG, Cheng X. Denys-Drash syndrome associated WT1 glutamine 369 mutants have altered sequence-preferences and altered responses to epigenetic modifications. Nucleic Acids Res 44:10165-10176 (2016). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.