DNA Binding Site

Accessions: comFA_1 (DBTBS 1.0)
Names: comF-P1, comFA_1
Organisms: Bacillus subtilis
Libraries: DBTBS 1.0 1
1 Sierro N, Makita Y, de Hoon M, Nakai K. DBTBS: a database of transcriptional regulation in Bacillus subtilis containing upstream intergenic conservation information. Nucleic acids research 36:D93-6 (2008). [Pubmed]
Length: 30
Sequence: ataaggccAAATctccgTTTTtagagcgga
Binding TFs: ComK (Basic membrane protein)
Binding Motifs: ComK_1 AAAA
ComK_2 TTTT
Publications: Hamoen L.W, Van Werkhoven A.F, Bijlsma J.J, Dubnau D, Venema G. The competence transcription factor of Bacillus subtilis recognizes short A/T-rich sequences arranged in a unique, flexible pattern along the DNA helix. Genes & development 12:1539-50 (1998). [Pubmed]

van Sinderen D, Luttinger A, Kong L, Dubnau D, Venema G, Hamoen L. comK encodes the competence transcription factor, the key regulatory protein for competence development in Bacillus subtilis. Molecular microbiology 15:455-62 (1995). [Pubmed]

Londoño-Vallejo J.A, Dubnau D. comF, a Bacillus subtilis late competence locus, encodes a protein similar to ATP-dependent RNA/DNA helicases. Molecular microbiology 9:119-31 (1993). [Pubmed]

Liu J, Zuber P. A molecular switch controlling competence and motility: competence regulatory factors ComS, MecA, and ComK control sigmaD-dependent gene expression in Bacillus subtilis. Journal of bacteriology 180:4243-51 (1998). [Pubmed]

Ogura M, Yamaguchi H, Kobayashi K, Ogasawara N, Fujita Y, Tanaka T. Whole-genome analysis of genes regulated by the Bacillus subtilis competence transcription factor ComK. Journal of bacteriology 184:2344-51 (2002). [Pubmed]

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