DNA Binding Site

						

			
Accessions: AACCGTTA (UniPROBE 20160601), PF0146.1.1 (JASPAR 2024), PF0146.1.18 (JASPAR 2024), PF0146.1.2 (JASPAR 2024), PF0146.1.20 (JASPAR 2024), PF0146.1.9 (JASPAR 2024)

			
Organisms: Homo sapiens
Libraries: UniPROBE 20160601 1, JASPAR 2024 2
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 8
Sequence: AACCGTTA
Type: Heterodimer
Binding TFs: UP00608A (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
UP00608B (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Binding Motifs: UP00608A_1 wtawktrrdACCGTTAymygkkk
UP00608B_1 rwywtvyArmTAACGGwywmayc
PF0146.1 rrCCGTTA
			
Publications: Barrera LA, Vedenko A, Kurland JV, Rogers JM, Gisselbrecht SS, Rossin EJ, Woodard J, Mariani L, Kock KH, Inukai S, Siggers T, Shokri L, Gordân R, Sahni N, Cotsapas C, Hao T, Yi S, Kellis M, Daly MJ, Vidal M, Hill DE, Bulyk ML. Survey of variation in human transcription factors reveals prevalent DNA binding changes. Science 351:1450-4 (2016). [Pubmed]


Xie X, Lu J, Kulbokas E.J, Golub T.R, Mootha V, Lindblad-Toh K, Lander E.S, Kellis M. Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals. Nature 434:338-45 (2005). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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