DNA Binding Site
| Accessions: | 1l1m_C (3D-footprint 20231221), 2kei_C (3D-footprint 20231221) |
| Organisms: | Escherichia coli, strain K12 |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Length: | 23 |
| Sequence: | GAATTGTGAGCGGATAACAATTT |
| Binding TFs: | 1l1m_B / 2kei_B (Bacterial regulatory proteins, lacI family) |
| Binding Motifs: | 1l1m_AB TTGTTATCCGCTCACAA 1l1m_B TTGTTATCCG 2kei_AB TGTTATCCGCTCACAA 2kei_B TGTTATACG |
| Publications: | Kalodimos C.G, Bonvin A.M, Salinas R.K, Wechselberger R, Boelens R, Kaptein R. Plasticity in protein-DNA recognition: lac repressor interacts with its natural operator 01 through alternative conformations of its DNA-binding domain. The EMBO journal 21:2866-76 (2002). [Pubmed] Romanuka J, Folkers G.E, Biris N, Tishchenko E, Wienk H, Bonvin A.M, Kaptein R, Boelens R. Specificity and affinity of Lac repressor for the auxiliary operators O2 and O3 are explained by the structures of their protein-DNA complexes. Journal of molecular biology 390:478-89 (2009). [Pubmed] |
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