DNA Binding Site

						

			
Accessions: CCCCGCGG (UniPROBE 20160601), MA2176.1.13 (JASPAR 2024)

			
Organisms: Mus musculus, Saccharomyces cerevisiae, Caenorhabditis elegans
Libraries: UniPROBE 20160601 1, JASPAR 2024 2
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]

2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 8
Sequence: CCCCGCGG
Type: Heterodimer
Binding TFs: UP00463A (Fungal Zn(2)-Cys(6) binuclear cluster domain, Fungal specific transcription factor domain )
UP00006A (Zinc finger, C2H2 type, Zinc-finger double-stranded RNA-binding, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
UP00057A (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
UP00102A (Zinc finger, C2H2 type, Zinc-finger of C2H2 type, Zinc-finger double domain, C2H2-type zinc finger)
Q18711 (Helix-loop-helix DNA-binding domain)
Q18711
Binding Motifs: UP00006A_1 smCCCCCgGGGGggt
UP00057A_1 bmCCCCCgGGGGggt
UP00102A_1 smCCCCcgGGGGGg
UP00006A_2 kwdCaCAGCAkGmsa
UP00057A_2 ycdCvCAGCAkGara
UP00102A_2 ymdCrCAGCAkGmrw
UP00463A_1 rcsbckwTCCGCGGAAmrggrs
MA2176.1 cCACGTGg
			
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]


Grove C.A, De Masi F, Barrasa M.I, Newburger D.E, Alkema M.J, Bulyk M.L, Walhout A.J. A multiparameter network reveals extensive divergence between C. elegans bHLH transcription factors. Cell 138:314-27 (2009). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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