DNA Binding Motif
| Accessions: | 5uan_AB (3D-footprint 20231221) |
| Names: | Retinoic acid receptor RXR-alpha |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Description: | Crystal structure of multi-domain RAR-beta-RXR-alpha heterodimer on DNA |
| Length: | 9 |
| Consensus: | GGtCannGG |
| Weblogo: |  |
| PSSM: | P0 A C G T 01 0 0 96 0 G 02 0 0 96 0 G 03 16 13 13 54 t 04 0 96 0 0 C 05 54 16 13 13 a 06 24 24 24 24 n 07 24 24 24 24 n 08 0 0 96 0 G 09 0 0 96 0 G |
| Type: | Heterodimer |
| Binding TFs: | 5uan_A (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains)) 5uan_B (Ligand-binding domain of nuclear hormone receptor, Zinc finger, C4 type (two domains)) |
| Binding Sites: | 5uan_E 5uan_F |
| Publications: | Chandra V, Wu D, Li S, Potluri N, Kim Y, Rastinejad F. The quaternary architecture of RARβ-RXRα heterodimer facilitates domain-domain signal transmission. Nat Commun 8:868 (2017). [Pubmed] |
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