DNA Binding Motif

						

			
Accessions: GCM1_SPDEF_2_3 (HumanTF2 1.0)

			
Names: GCM1_SPDEF
Organisms: Homo sapiens
Libraries: HumanTF2 1.0 1
1 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]
Notes: Site type: heterodimeric; Experiment type: CAP-SELEX
Length: 13
Consensus: rTgmkGGcGGAtg
Weblogo: 
PSSM: P0      A      C      G      T
01    463    147    370    117      r
02     48     52     97    834      T
03    310    112    834     21      g
04    234    331    153    116      m
05     57     41    584    250      k
06     16     12    834     30      G
07      0     37    834      9      G
08    155    834    140    183      c
09     28     21    834     42      G
10     41     39    834     81      G
11    834    101    168     70      A
12    247     79     95    587      t
13    205    274    834    163      g
Type: Heterodimer
Binding TFs: GCM1_TF1 (GCM motif protein)
SPDEF_TF2 (Ets-domain, Sterile alpha motif (SAM)/Pointed domain)
			
Publications: Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed]

	
			


			

				

				
				
				
				

			

			

		

	
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